AZD1446

DRUG11 trials

Sponsors

AstraZeneca

Conditions

Adult ADHDAlzheimer´s DiseaseCognitionHealthyMild to Moderate Alzheimer's Disease

Phase 1

Study to Assess Safety, Tolerability and Pharmacokinetics After Single Doses of AZD1446 to Healthy Volunteers

CompletedNCT00803855

AstraZenecaHealthy

Start: 2008-12-31End: 2009-04-30Updated: 2009-05-15

Positron Emission Tomography (PET) Study

CompletedNCT00886067

AstraZenecaHealthy

Start: 2009-04-30End: 2009-08-31Updated: 2009-09-10

Study to Investigate Safety, Tolerability and Pharmacokinetics With Single and Multiple Ascending Doses of AZD1446

CompletedNCT00902993

AstraZenecaHealthy

Start: 2009-04-30End: 2009-09-30Target: 80Updated: 2009-10-01

A Study to Investigate Safety, Tolerability and Pharmacokinetics of AZD1446 Administered for 4 Weeks in Elderly Healthy Volunteers

CompletedNCT00997308

AstraZenecaHealthy

Start: 2009-10-31End: 2009-12-31Updated: 2010-01-22

Study to Assess Safety, Tolerability and Pharmacokinetics After Single and Multiple Doses of AZD1446 to Japanese Subject

CompletedNCT01021189

AstraZenecaHealthy

Start: 2009-12-31End: 2010-06-30Updated: 2010-06-10

A Healthy Volunteer Study to Evaluate Reversibility of Induced Impairment of Cognition

CompletedNCT01044342

AstraZenecaCognition

Start: 2009-12-31End: 2010-04-30Target: 20Updated: 2010-05-10

A Bioavailability Study Comparing Modified-release Capsules and Immediate Release Capsules in Fed and Fasting Conditions

CompletedNCT01092299

AstraZenecaHealthy

Start: 2010-02-28End: 2010-07-31Updated: 2010-08-27

A Study to Assess the Safety, Tolerability and Pharmacokinetics of Modified-Release Formulations of AZD1446 After Oral Single and Repeated Doses

CompletedNCT01199315

AstraZenecaHealthy

Start: 2010-09-30End: 2010-12-31Updated: 2011-02-17

Phase 2

Study to Investigate the Efficacy and Tolerability of AZD1446 in Adult ADHD Patients.

CompletedNCT01012375

AstraZenecaAdult ADHD

Start: 2009-11-30End: 2010-08-31Updated: 2011-09-02

4 Week, Safety and Tolerability Study in Patients With Mild to Moderate Alzheimer's Disease

CompletedNCT01039701

AstraZenecaMild to Moderate Alzheimer's Disease

Start: 2009-12-31End: 2010-07-31Updated: 2010-08-11

To Evaluate Effects of AZD1446, Placebo and Donepezil in Patients With Alzheimer's Disease

TerminatedNCT01125683

AstraZenecaAlzheimer´s Disease

Start: 2010-06-30End: 2011-03-31Target: 40Updated: 2011-05-13