AZD0837

DRUG7 trials

Sponsors

AstraZeneca

Conditions

HealthyNonvalvular Atrial FibrillationPersistent or Permanent Non-valvular Atrial FibrillationPersistent or Permanent Nonvalvular Atrial Fibrillation

Phase 1

Excretion of Radiolabelled AZD0837

CompletedNCT00812643

AstraZenecaHealthy

Start: 2009-01-31End: 2009-02-28Target: 8Updated: 2009-03-11

Effect of Ketoconazole on Biliary Excretion of AZD0837

CompletedNCT00812344

AstraZenecaHealthy

Start: 2008-12-31End: 2009-03-31Target: 20Updated: 2010-12-03

Pharmacokinetics of Extended-Release Test- and Reference Formulations of AZD0837

CompletedNCT00878618

AstraZenecaHealthy

Start: 2009-04-30End: 2009-05-31Target: 36Updated: 2009-06-03

AZD0837 Extended Release (ER) Japan Study

CompletedNCT00904800

AstraZenecaHealthy

Start: 2009-05-31End: 2009-06-30Target: 36Updated: 2009-07-13

Phase 2

Atrial Fibrillation (AF) Patients Not Taking Vitamin-K Antagonist (VKA)

CompletedNCT00623779

AstraZenecaPersistent or Permanent Non-valvular Atrial Fibrillation

Start: 2007-10-31End: 2008-10-31Updated: 2012-03-23

Long-term Safety in Atrial Fibrillation Patients

CompletedNCT00645853

AstraZenecaPersistent or Permanent Nonvalvular Atrial Fibrillation

Start: 2007-10-31End: 2009-05-31Updated: 2012-03-23

Prevention of Stroke and Systemic Embolic Events in Patients With Atrial Fibrillation

CompletedNCT00684307

AstraZenecaNonvalvular Atrial Fibrillation

Start: 2007-02-28End: 2008-06-30Updated: 2012-03-23

Related Papers

Oral direct thrombin inhibitor AZD0837 for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation: a Phase II study of AZD0837 in patients who are appropriate for but unable or unwilling to take vitamin K antagonist therapy.

2010-12-1820 citations

Oral direct thrombin inhibitor AZD0837 for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation: a randomized dose-guiding, safety, and tolerability study of four doses of AZD0837 vs. vitamin K antagonists.

2009-08-1863 citations