AZD0292

DRUG4 trials

Sponsors

AstraZeneca

Conditions

Bronchiectasis With Pseudomonas Aeruginosa ColonizationHealthy ParticipantsHealthy Participants Study

Phase 1

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of a Single Ascending Dose of AZD0292 In Healthy Participants

CompletedNCT06311760

AstraZenecaHealthy Participants Study

Start: 2024-04-09End: 2025-02-20Updated: 2025-02-27

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of a Single Ascending Dose of AZD0292 in Healthy Japanese Participants

CompletedNCT07222254

AstraZenecaHealthy Participants

Start: 2025-12-12End: 2026-07-30Updated: 2026-08-20

Phase 2

A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization

RecruitingNCT07088926

AstraZenecaBronchiectasis With Pseudomonas Aeruginosa Colonization

Start: 2025-11-06End: 2028-06-14Target: 435Updated: 2026-09-16

A Study of AZD0292 in Chinese Participants With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization

RecruitingNCT07774403

AstraZenecaBronchiectasis With Pseudomonas Aeruginosa Colonization

Start: 2026-06-24End: 2028-06-06Target: 84Updated: 2026-08-19