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axillary lymph node dissection (ALND)

PROCEDURE3 trials

Sponsors

Alliance for Clinical Trials in Oncology, Zhejiang Cancer Hospital, University Hospital, Basel, Switzerland

Conditions

Breast CancerLymph Node MetastasesPredictive Cancer ModelStage II Breast CancerStage IIIA Breast Cancer

Phase 3

Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy
Active, not recruitingNCT01901094
Alliance for Clinical Trials in OncologyStage II Breast Cancer, Stage IIIA Breast Cancer
Start: 2014-02-24End: 2031-01-31Updated: 2026-08-31

Unknown Phase

A Prospective Validation Cohort Study of a Prediction System on nSLN Metastasis in Early Breast Cancer
NCT03280134
Zhejiang Cancer HospitalBreast Cancer, Lymph Node Metastases, Predictive Cancer Model
Start: 2018-10-15End: 2020-06-30Target: 388Updated: 2019-06-04
Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery
RecruitingNCT07140172
University Hospital, Basel, SwitzerlandBreast Cancer
Start: 2026-01-01End: 2037-12-01Target: 1060Updated: 2026-08-07

Related Papers

Abstract RF2-01: Factors Influencing Additional Nodal Disease and Pathologic Nodal Upstaging with Axillary Dissection in Patients with Residual Node-Positive Breast Cancer After Neoadjuvant Chemotherapy Enrolled on Alliance A011202 Clinical Trial
Clinical Cancer Research2025-06-137 citations
Nodal Burden and Oncologic Outcomes in Patients With Residual Isolated Tumor Cells After Neoadjuvant Chemotherapy (ypN0i+): The OPBC-05/ICARO Study
Journal of Clinical Oncology2024-11-0727 citations
Combined analysis of the MF18‐02/MF18‐03 NEOSENTITURK studies: ypN‐positive disease does not necessitate axillary lymph node dissection in patients with breast cancer with a good response to neoadjuvant chemotherapy as long as radiotherapy is provided
Cancer2024-10-306 citations
Disease extent according to baseline [18F]fluorodeoxyglucose PET/CT and molecular subtype: prediction of axillary treatment response after neoadjuvant systemic therapy for breast cancer
British journal of surgery2024-08-302 citations
Impact of Imaging-Guided Localization on Performance of Tailored Axillary Surgery in Patients with Clinically Node-Positive Breast Cancer: Prospective Cohort Study Within TAXIS (OPBC-03, SAKK 23/16, IBCSG 57-18, ABCSG-53, GBG 101)
Annals of Surgical Oncology2023-10-3016 citations
Protocol for the T-REX-trial: tailored regional external beam radiotherapy in clinically node-negative breast cancer patients with 1-2 sentinel node macrometastases – an open, multicentre, randomised non-inferiority phase 3 trial
BMJ Open2023-09-0117 citations
Axillary lymph node dissection versus radiotherapy in breast cancer with positive sentinel nodes after neoadjuvant therapy (ADARNAT trial)
Frontiers in Oncology2023-08-0920 citations
Optimal Management for Residual Disease Following Neoadjuvant Systemic Therapy.
2021-07-0215 citations
Surgical Management of the Axilla in Clinically Node-Positive Breast Cancer Patients Converting to Clinical Node Negativity through Neoadjuvant Chemotherapy: Current Status, Knowledge Gaps, and Rationale for the EUBREAST-03 AXSANA Study.
2021-03-29112 citations
Abstract SP023: State of the art treatment for neoadjuvant/adjuvant triple negative breast cancer
Cancer Research2021-02-15
Multidisciplinary considerations in the treatment of triple‐negative breast cancer
CA A Cancer Journal for Clinicians2020-09-2815 citations
A Prospective Validation Cohort Study of a Prediction Model on Non-sentinel Lymph Node Involvement in Early Breast Cancer.
2019-10-284 citations
A prospective validation cohort study of a prediction model on non-sentinel lymph node involvement in early breast cancer.
Journal of Clinical Oncology2019-05-201 citations
Tailored axillary surgery with or without axillary lymph node dissection followed by radiotherapy in patients with clinically node-positive breast cancer (TAXIS): study protocol for a multicenter, randomized phase-III trial.
2018-12-04108 citations
Postmastectomy Radiation Therapy
Oncology Times2016-12-252 citations