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Autologous regulatory T cell product
BIOLOGICAL
2 trials
Sponsors
Guy's and St Thomas' NHS Foundation Trust
Conditions
End-stage Liver Disease
End-stage Renal Failure
Phase 1
The ONE Study UK Treg Trial
Completed
NCT02129881
Guy's and St Thomas' NHS Foundation Trust
End-stage Renal Failure
Start: 2014-04-30
End: 2017-03-23
Updated: 2019-01-25
Safety and Efficacy Study of Regulatory T Cell Therapy in Liver Transplant Patients
Completed
NCT02166177
Guy's and St Thomas' NHS Foundation Trust
End-stage Liver Disease
Start: 2014-06-30
End: 2018-01-22
Updated: 2019-01-10
Related Papers
Regulatory T cell therapy is associated with distinct immune regulatory lymphocytic infiltrates in kidney transplants.
2024-12-27
7 citations
Intranodal Sirolimus Induces Regulatory T Cells in Human Hepatic Lymph Nodes via Interleukin 10 Signaling
Liver Transplantation
2021-06-16
6 citations
Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.
2020-05-01
321 citations