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autologous immunoglobulin idiotype-KLH conjugate vaccine

BIOLOGICAL9 trials

Sponsors

Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium, Genitope Corporation, Favrille, University of Texas Southwestern Medical Center

Conditions

Brain and Central Nervous System TumorsLymphomaLymphoproliferative DisorderNon-Hodgkin's LymphomaRefractory Multiple MyelomaSmall Intestine CancerStage I Multiple MyelomaStage II Multiple Myeloma

Phase 1

Vaccine Therapy in Treating Patients With Multiple Myeloma Who Have Undergone Stem Cell Transplantation
CompletedNCT00002787
Fred Hutchinson Cancer Research Center/University of Washington Cancer ConsortiumRefractory Multiple Myeloma, Stage III Multiple Myeloma, Stage II Multiple Myeloma +1
Start: 1996-03-31Updated: 2019-05-06

Phase 2

Vaccine Therapy and Sargramostim After Rituximab in Treating Patients With Refractory or Progressive Non-Hodgkin's Lymphoma
CompletedNCT00071955
Genitope CorporationLymphoma
Start: 2003-03-31End: 2009-01-31Updated: 2013-12-19
Vaccine Therapy and GM-CSF in Treating Patients With Progressive Non-Hodgkin's Lymphoma
TerminatedNCT00104819
FavrilleLymphoma
Start: 2004-09-30Target: 238Updated: 2013-08-02
Rituximab, Vaccine Therapy, and GM-CSF in Treating Patients With Non-Hodgkin's Lymphoma
NCT00258336
FavrilleLymphoma
Start: 2004-08-31Target: 56Updated: 2014-01-10
Personalized Active Immunotherapy (Vaccine Therapy) and Sargramostim Given After Standard of Care Treatment With Rituximab and Chemotherapy for Initial Treatment With Lymphoma
TerminatedNCT00510471
Genitope CorporationNon-Hodgkin's Lymphoma
Start: 2007-05-31Updated: 2008-03-18
Vaccine Therapy and GM-CSF in Treating Patients With CNS Lymphoma
WithdrawnNCT00621036
University of Texas Southwestern Medical CenterBrain and Central Nervous System Tumors, Lymphoma, Lymphoproliferative Disorder +1
Start: 2007-10-19End: 2008-12-08Updated: 2018-11-26

Phase 3

Combination Chemotherapy Followed By Vaccine Therapy Plus Sargramostim in Treating Patients With Stage III or Stage IV Non-Hodgkin's Lymphoma
NCT00017290
Genitope CorporationLymphoma
Start: 2000-11-30Updated: 2013-12-04
Vaccine Therapy and Sargramostim Compared With Placebo and Sargramostim Following Rituximab in Treating Patients With Non-Hodgkin's Lymphoma
TerminatedNCT00089115
FavrilleLymphoma
Start: 2004-07-31Updated: 2013-08-02
GM-CSF With or Without Vaccine Therapy After Combination Chemotherapy and Rituximab as First-Line Therapy in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma
SuspendedNCT00324831
FavrilleLymphoma
Target: 480Updated: 2013-12-18