Astatine At 211 Anti-CD45 Monoclonal Antibody BC8-B10
Sponsors
Fred Hutchinson Cancer Center
Conditions
Acute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAcute Myeloid Leukemia in RemissionChronic Myelomonocytic LeukemiaHematopoietic and Lymphoid Cell NeoplasmMyelodysplastic Syndrome With Excess BlastsNon-Malignant NeoplasmRecurrent Acute Lymphoblastic Leukemia
Phase 1
211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome
RecruitingNCT03670966
Start: 2019-07-10End: 2029-03-20Target: 30Updated: 2025-10-16
Total Body Irradiation and Astatine-211-Labeled BC8-B10 Monoclonal Antibody for the Treatment of Nonmalignant Diseases
RecruitingNCT04083183
Start: 2020-06-16End: 2028-01-09Target: 40Updated: 2025-12-18