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Ascorbate

DRUG11 trials

Sponsors

Beersheva Mental Health Center, Joseph J. Cullen, MD, FACS, Joseph J. Cullen, Mohammed Milhem, MBBS, Mohammed Milhem

Conditions

Acute SchizophreniaBone SarcomaGBMGlioblastomaGlioblastoma MultiformeMetastatic Bone SarcomaMetastatic Bone TumorMetastatic Pancreatic Adenocarcinoma

Early Phase 1

Gemcitabine Plus Ascorbate for Sarcoma in Adults (Pilot)
Active, not recruitingNCT04634227
University of IowaBone Sarcoma, Metastatic Bone Tumor, Sarcoma +2
Start: 2020-11-24End: 2026-12-31Updated: 2025-05-04
Gemcitabine With Ascorbate Including Adolescents
WithdrawnNCT04877587
David DickensBone Sarcoma, Metastatic Bone Sarcoma, Metastatic Soft-tissue Sarcoma +3
Start: 2023-01-31End: 2025-05-31Updated: 2023-02-22

Phase 1

A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme
CompletedNCT01752491
Joseph J. Cullen, MD, FACSGBM, Glioblastoma, Glioblastoma Multiforme
Start: 2013-04-01End: 2019-11-15Updated: 2024-12-20
Gemcitabine, Ascorbate, Radiation Therapy for Pancreatic Cancer, Phase I
CompletedNCT01852890
Joseph J. CullenPancreatic Neoplasms
Start: 2014-01-31End: 2025-10-14Updated: 2025-10-24
High Dose Ascorbate With Preoperative Radiation in Patients With Locally Advanced Soft Tissue Sarcomas
CompletedNCT03508726
Mohammed MilhemSoft Tissue Sarcoma
Start: 2019-06-27End: 2024-06-02Updated: 2024-06-27
High Dose Ascorbic Acid for Plasma Cell Disorders
CompletedNCT03602235
Christopher StrouseMultiple Myeloma
Start: 2019-03-05End: 2025-09-03Updated: 2025-10-21

Phase 2

Gemcitabine Plus Ascorbate for Sarcoma in Adults
TerminatedNCT03468075
Mohammed Milhem, MBBSBone Sarcoma, Metastatic Bone Tumor, Sarcoma +2
Start: 2018-07-11End: 2020-10-19Updated: 2020-12-10
A Clinical Trial Evaluating the Effect of Pharmacological Ascorbate on Radiation Therapy for Pancreatic Cancer Patients
WithdrawnNCT03541486
Joseph J. Cullen, MD, FACSPancreatic Neoplasm
Start: 2025-12-31End: 2030-12-31Updated: 2025-03-10
Vitamin C to Quality of Life in Patients With Terminal Stage Pancreatic Cancer
RecruitingNCT06018896
Fudan UniversityMetastatic Pancreatic Cancer, Terminal Cancer
Start: 2023-08-25End: 2026-08-15Target: 20Updated: 2024-06-06

Phase 3

Vitamin C to Chemotherapy Related Anemia in Pancreatic Cancer
Active, not recruitingNCT06018883
Fudan UniversityMetastatic Pancreatic Adenocarcinoma
Start: 2023-08-20End: 2026-08-15Target: 100Updated: 2025-08-07

Phase 4

Treatment of Acute Schizophrenia With Vitamin Therapy
CompletedNCT00140166
Beersheva Mental Health CenterAcute Schizophrenia
Start: 2005-07-31End: 2008-05-31Target: 55Updated: 2009-11-25

Related Papers

Efficacy of vitamin C on chemotherapy-related anemia in pancreatic cancer: study protocol for a randomized controlled trial.
2024-07-29