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Artesunate pessary

DRUG2 trials

Sponsors

UNC Lineberger Comprehensive Cancer Center

Conditions

Cervical PrecancerCervix CancerCervix Intraepithelial Neoplasia Grade 3Cervix NeoplasmCervix; Intraepithelial Neoplasia, Grade ICervix; Intraepithelial Neoplasia, Grade IIPrecancerous Conditions

Phase 1

Artesunate Pessaries (Vaginal Inserts) for Cervical Precancer in Kenya
CompletedNCT06165614
UNC Lineberger Comprehensive Cancer CenterCervical Precancer, Cervix Cancer, Cervix Neoplasm +1
Start: 2024-03-04End: 2025-04-10Updated: 2025-08-19
Pharmacokinetics of Intravaginal, Self-administered Artesunate Vaginal Pessaries Among Women in Kenya
CompletedNCT06263582
UNC Lineberger Comprehensive Cancer CenterCervix Cancer, Cervix Intraepithelial Neoplasia Grade 3, Cervix; Intraepithelial Neoplasia, Grade I +1
Start: 2024-05-29End: 2024-08-14Updated: 2025-08-19

Related Papers

Abstract 82: Women’s Experiences with and Acceptability of Intravaginal, Self-Administered Artesunate Pessaries of Cervical Precancer Treatment in Kenya
Cancer Epidemiology Biomarkers & Prevention2025-12-01
Abstract 68: Phase I Study of Self-Administered Artesunate Pessaries for Treatment of Cervical Precancer in HIV- Positive and HIV-Negative Women in Kenya
Cancer Epidemiology Biomarkers & Prevention2025-12-01
Feasibility of Intravaginal Artesunate as an Adjuvant HPV & Cervical Precancer Treatment Among Women Living With HIV in Kenya: Study Protocol for a Phase II Clinical Trial
Cancer Control2025-08-01