Artemether-lumefantrine (AL)

DRUG11 trials

Sponsors

Institute of Tropical Medicine, Belgium, University of Copenhagen, Centers for Disease Control and Prevention, Medecins Sans Frontieres, Netherlands, Liverpool School of Tropical Medicine

Conditions

Covid-19FeverGestational Age and Weight ConditionsHIV InfectionsHivLow BirthweightMALARIA, FALCIPARUMMalaria

Phase 3

Evaluation of 4 Artemisinin-based Combinations for Treating Uncomplicated Malaria in African Children

CompletedNCT00393679

Institute of Tropical Medicine, BelgiumFever, Malaria

Start: 2007-07-31End: 2009-12-31Updated: 2014-02-03

Malaria as a Risk Factor for COVID-19 in Western Kenya and Burkina Faso

CompletedNCT04695197

Liverpool School of Tropical MedicineCovid-19, Malaria

Start: 2021-01-08End: 2024-02-20Updated: 2024-02-23

A Study to Find Out if a Combination of 3 Medicines for the Treatment of Malaria Works as Well and is as Safe and Tolerable as Combinations of 2 Medicines

RecruitingNCT05951595

University of OxfordUncomplicated Plasmodium Falciparum Malaria

Start: 2025-09-11End: 2026-07-31Target: 1680Updated: 2025-11-18

Phase 4

Interactions Between Artemether-lumefantrine and Antiretrovirals in HIV-patients With Uncomplicated Malaria in Tanzania

CompletedNCT00885287

University of CopenhagenHIV Infections, Malaria, Falciparum

Start: 2009-07-31End: 2013-01-31Updated: 2013-01-16

In Vivo Efficacy of Artemether-Lumefantrine and Artesunate-Amodiaquine for Uncomplicated P. Falciparum Malaria

CompletedNCT02637128

Centers for Disease Control and PreventionMALARIA, FALCIPARUM

Start: 2014-03-31End: 2014-07-31Updated: 2015-12-22

Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Uncomplicated Malaria in South Kivu, DR Congo

CompletedNCT02741024

Medecins Sans Frontieres, NetherlandsMalaria

Start: 2013-10-31End: 2014-12-31Updated: 2016-04-18

Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics

RecruitingNCT05757167

Duke UniversityGestational Age and Weight Conditions, Low Birthweight, Malaria,Falciparum +6

Start: 2023-11-06End: 2027-02-01Target: 2500Updated: 2026-01-20

OPTImizing Malaria And HIV Treatment in a Shifting Landscape in Africa

RecruitingNCT06967519

Yale UniversityHiv, Malaria

Start: 2025-12-18End: 2027-12-01Target: 380Updated: 2026-02-04

Unknown Phase

Artemisinin based Combination therapy Trial

Active, not recruitingPACTR201803003018369

Laboratorios SALVAT, S.A.,Malaria

Start: 2013-09-27Updated: 2026-01-27

Therapeutic Efficacy Study of AL and DP in Western Kenya

CompletedNCT05060198

Kenya Medical Research InstituteMalaria,Falciparum

Start: 2016-06-17End: 2020-12-31Updated: 2021-09-29

Impact of Malaria Mass Drug Administration on Malaria Prevalence in Under 15 Children and Pregnant Women

CompletedNCT07358767

Noguchi Memorial Institute for Medical ResearchMalaria

Start: 2021-07-01End: 2023-03-31Updated: 2026-01-22

Related Papers

Artemether-lumefantrine versus pyronaridine-artesunate for the treatment of malaria in patients with mild to moderate COVID-19 in Kenya and Burkina Faso: a randomised open-label trial (MALCOV).

2026-01-03

In vivo efficacy of artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated falciparum malaria: an open-randomized, non-inferiority clinical trial in South Kivu, Democratic Republic of Congo.

2016-09-0616 citations

Efficacy of quinine, artemether-lumefantrine and dihydroartemisinin-piperaquine as rescue treatment for uncomplicated malaria in Ugandan children.

2013-01-2225 citations

A head-to-head comparison of four artemisinin-based combinations for treating uncomplicated malaria in African children: a randomized trial.

2011-11-08120 citations