Artemether + Lumefantrine

DRUG4 trials

Sponsors

GlaxoSmithKline, Thierry Buclin, Strathmore University, Curtin University

Conditions

MalariaMalaria FalciparumMalaria, VivaxUncomplicated Malaria

Phase 1

A Study to Evaluate the Pharmacokinetics of a Single Dose of Tafenoquine Co-administered With Either Artemether + Lumefantrine or Dihydroartemisinin + Piperaquine Tetraphosphate

CompletedNCT02184637

GlaxoSmithKlineMalaria, Vivax

Start: 2014-07-31End: 2015-04-08Updated: 2017-07-13

Phase 4

Lumefantrine in Venous Plasma Versus Dried Capillary Blood Spot

CompletedNCT02742285

Thierry BuclinMalaria

Start: 2016-05-31End: 2016-09-30Updated: 2018-01-16

Investigating the Pharmacology of Tafenoquine in Papua New Guinean Children With Uncomplicated Malaria

Not yet recruitingNCT07403643

Curtin UniversityUncomplicated Malaria

Start: 2026-04-01End: 2026-12-01Target: 60Updated: 2026-02-12

Unknown Phase

Health Systems Implementation and Molecular Surveillance of Multiple First-Line Treatments for Uncomplicated Malaria in Western Kenya

CompletedNCT07362498

Strathmore UniversityMalaria Falciparum

Start: 2020-06-01End: 2024-01-31Updated: 2026-01-23

Related Papers

Pharmacokinetic Interactions between Tafenoquine and Dihydroartemisinin-Piperaquine or Artemether-Lumefantrine in Healthy Adult Subjects

Antimicrobial Agents and Chemotherapy2016-10-0431 citations