ARRY-371797, p38 inhibitor; oral

DRUG7 trials

Sponsors

Pfizer, Array Biopharma, now a wholly owned subsidiary of Pfizer

Conditions

Ankylosing SpondylitisDental PainHealthyLMNA-Related Dilated CardiomyopathyOsteoarthritis of the KneeRheumatoid Arthritis

Phase 1

A Study of ARRY-371797 in Patients With Rheumatoid Arthritis

CompletedNCT00729209

Array Biopharma, now a wholly owned subsidiary of PfizerRheumatoid Arthritis

Start: 2008-07-31End: 2009-04-30Updated: 2020-09-21

A Safety Study of ARRY-371797 in Healthy Subjects

CompletedNCT00790049

Array Biopharma, now a wholly owned subsidiary of PfizerHealthy

Start: 2008-10-31End: 2009-01-21Updated: 2022-05-05

Phase 2

A Study of ARRY-371797 in Subjects Undergoing Third Molar Extraction

CompletedNCT00542035

PfizerDental Pain

Start: 2007-11-11End: 2008-02-11Updated: 2021-02-21

A Study of ARRY-371797 in Subjects Undergoing Third Molar Extraction

CompletedNCT00663767

PfizerDental Pain

Start: 2008-04-07End: 2008-06-20Updated: 2021-02-09

A Study of ARRY-371797 in Patients With Active Ankylosing Spondylitis

TerminatedNCT00811499

PfizerAnkylosing Spondylitis

Start: 2008-12-16End: 2009-09-29Updated: 2020-10-19

A Study of ARRY-371797 in Patients With Osteoarthritis of the Knee

CompletedNCT01366014

PfizerOsteoarthritis of the Knee

Start: 2011-06-30End: 2012-06-30Updated: 2020-10-14

A Study of ARRY-371797 in Patients With LMNA-Related Dilated Cardiomyopathy

CompletedNCT02057341

PfizerLMNA-Related Dilated Cardiomyopathy

Start: 2014-02-28End: 2016-05-31Updated: 2020-10-14

Related Papers

REALM-DCM: A Phase 3, Multinational, Randomized, Placebo-Controlled Trial of ARRY-371797 in Patients With Symptomatic <i>LMNA</i> -Related Dilated Cardiomyopathy

Circulation Heart Failure2024-07-0117 citations

Long-Term Effectiveness of ARRY-371797 in People With Dilated Cardiomyopathy and a Faulty LMNA Gene: A Plain Language Summary

Future Cardiology2023-03-014 citations

Plain Language Summary of Publication of the safety and efficacy of ARRY-371797 in people with dilated cardiomyopathy and a faulty <i>LMNA</i> gene.

2023-01-312 citations

Efficacy and Safety of ARRY-371797 in <i>LMNA</i> -Related Dilated Cardiomyopathy: A Phase 2 Study

Circulation Genomic and Precision Medicine2022-12-1416 citations