Armisarte 25 mg/ml concentrate for solution for infusion
Sponsors
AstraZeneca AB, Antwerp University Hospital, Astrazeneca AB, Regeneron Pharmaceuticals Inc., Fondazione Ricerca Traslazionale
Conditions
NSCLC non-small cell lung cancerNon-small Cell Lung CancerPatients with histologically or cytologically documented non-squamous NSCLC with completely resectable (Stage II - IIIB N2) diseaseUnresectable Non-small Cell Lung Cancerinoperable pleural mesothelioma
Phase 2
A Phase II, Open-label, Single-arm Study of Osimertinib as Induction Therapy Prior to CRT and Maintenance Osimertinib in Patients with Epidermal Growth Factor Receptor (EGFR) Mutation-positive, Stage III, Unresectable Non-small Cell Lung Cancer (NEOLA)
Active, not recruitingCTIS2023-507798-16-00
Start: 2024-04-16Target: 16Updated: 2025-04-28
NEoadjuvant Chemotherapy and Immunotherapy for a selected group of inoperable pleural Mesothelioma patients (NECIM): a feasibility study
RecruitingCTIS2023-504302-11-02
Start: 2025-07-22Target: 37Updated: 2025-11-21
A Randomized phase II trial of Cemiplimab plus OSE2101 (TEDOPI®) as maintenance therapy in ctDNA positive NSCL. The Cemited study.
RecruitingCTIS2024-519262-42-00
Start: 2025-07-15Target: 90Updated: 2025-08-13
Phase 3
A Phase III, Randomized, Controlled, Multi-center, 3-Arm Study of Neoadjuvant Osimertinib as Monotherapy or in Combination with Chemotherapy versus Standard of Care Chemotherapy Alone for the Treatment of Patients with Epidermal Growth Factor Receptor Mutation Positive, Resectable Non-small Cell Lung Cancer (NeoADAURA)
Active, not recruitingCTIS2022-502606-33-00
Start: 2021-02-26Target: 40Updated: 2025-07-23
A Global, Randomized, Phase 3, Open-Label Study of REGN2810 (Anti-PD-1 Antibody) versus Platinum-Based Chemotherapy in First-Line Treatment of Patients with Advanced or Metastatic PD-L1 + Non-Small Cell Lung Cancer
CompletedCTIS2024-515052-20-00
Start: 2017-09-20End: 2025-04-18Target: 68Updated: 2024-12-10
A Two-Part Randomized, Phase 3 Study of Combinations of Cemiplimab (Anti- PD-1 Antibody) and Platinum-based Doublet Chemotherapy in First-line Treatment of Patients with Advanced or Metastatic Non-Small Cell Lung Cancer
CompletedCTIS2024-515051-38-00
Start: 2018-07-20End: 2025-02-27Target: 117Updated: 2024-12-10