Arm 1: Routine Care

OTHER3 trials

Sponsors

Brigham and Women's Hospital, Harvard Pilgrim Health Care

Conditions

Abdominal (ABD) InfectionC. DifficileSkin and Soft Tissue (SST) Infection

Unknown Phase

Pre-emptive Prevention for Patients at High Risk for Hospital-onset Clostridioides Difficile

RecruitingNCT05389904

Brigham and Women's HospitalC. Difficile

Start: 2022-07-25End: 2026-08-01Target: 300Updated: 2026-03-04

INSPIRE Trial for Abdominal Infections

CompletedNCT05423743

Harvard Pilgrim Health CareAbdominal (ABD) Infection

Start: 2023-01-01End: 2025-05-09Updated: 2025-08-15

INSPIRE Trial for Skin and Soft Tissue Infections

CompletedNCT05423756

Harvard Pilgrim Health CareSkin and Soft Tissue (SST) Infection

Start: 2023-01-01End: 2024-05-09Updated: 2026-08-28

Related Papers

Improving Empiric Antibiotic Selection for Patients With Cancer Hospitalized With Infection

JAMA Network Open2026-06-10

Improving Empiric Antibiotic Selection for Patients Hospitalized With Abdominal Infection: The INSPIRE 4 Cluster Randomized Clinical Trial.

2025-07-014 citations

Improving Empiric Antibiotic Selection for Patients Hospitalized With Skin and Soft Tissue Infection: The INSPIRE 3 Skin and Soft Tissue Randomized Clinical Trial.

2025-06-017 citations