Aramchol
Sponsors
Galmed Medical Reserch, Galmed Research and Development, Ltd., Galmed Pharmaceuticals Ltd, University of California, San Diego
Conditions
Fatty LiverGallstonesHIVHealthyHealthy VolunteersLiver DiseasesLiver FibrosesMetabolic Syndrome
Phase 1
A Phase 1 Single and Multiple-Dose Study of Aramchol in Healthy Male Volunteers
CompletedNCT00776841
Start: 2008-09-30End: 2009-10-31Updated: 2010-11-03
Pharmacokinetics of Single and Multiple Escalating Doses of Aramchol and Food Effect in Healthy Volunteers
CompletedNCT02374437
Start: 2014-04-30End: 2014-12-31Updated: 2015-02-27
Pharmacokinetics of Single and Multiple Escalating Doses of Aramchol Administered Under Fed Conditions in Healthy Chinese Volunteers
CompletedNCT02803996
Start: 2016-05-31End: 2016-12-31Updated: 2016-12-21
Study of Potential for Drug Interactions Mediated by CYP3A4 Inhibition With Aramchol in Healthy Volunteers
CompletedNCT03760848
Start: 2018-11-12End: 2019-02-02Updated: 2019-08-22
Comparison of Aramchol Concentrations With Once or Twice Daily Dosing
CompletedNCT03774173
Start: 2018-12-08End: 2019-03-05Updated: 2019-08-09
An Open-Label, Two-Part Study Designed to Assess the Absolute Bioavailability and Mass Balance of Aramchol
CompletedNCT05874336
Start: 2020-06-17End: 2020-08-11Updated: 2023-05-24
Single and Multiple Dose Pharmacokinetics (PK) of Aramchol From an Aramchol Meglumine Tablet
RecruitingNCT07251712
Start: 2025-12-25End: 2026-10-10Target: 32Updated: 2026-09-10
Phase 2
Study of Aramchol in Patients With Fatty Liver Disease or Nonalcoholic Steatohepatitis
CompletedNCT01094158
Start: 2010-11-30End: 2012-01-31Target: 60Updated: 2012-01-31
A Clinical Trial to Evaluate the Efficacy and Safety of Two Aramchol Doses Versus Placebo in Patients With NASH
CompletedNCT02279524
Start: 2015-04-29End: 2018-05-22Updated: 2021-07-14
Medical Dissolution of Cholesterol Gallstones Using Oral Aramchol - A Proof of Concept Phase IIa Study
TerminatedNCT02325492
Start: 2014-10-31End: 2015-10-31Updated: 2015-10-05
Aramchol for HIV-associated Nonalcoholic Fatty Liver Disease and Lipodystrophy
CompletedNCT02684591
Start: 2016-01-31End: 2018-02-28Updated: 2020-07-17