Aprepitant 125 mg

DRUG5 trials

Sponsors

Merck Sharp & Dohme LLC, Albert Einstein College of Medicine, Nuformix Technologies Limited, Universitaire Ziekenhuizen KU Leuven, The First Affiliated Hospital of Zhengzhou University

Conditions

Chemotherapy Induced Nausea and VomitingChemotherapy-induced Nausea and VomitingHealthyPruritusThyroid Cancer

Phase 1

Relative Bioavailability of NXP001 Compared to Emend® in Healthy Volunteers

CompletedNCT03889366

Nuformix Technologies LimitedHealthy

Start: 2019-03-20End: 2019-04-30Updated: 2020-02-25

Phase 2

Low Dose Aprepitant for Patients Receiving Carboplatin

TerminatedNCT03237611

Albert Einstein College of MedicineChemotherapy-induced Nausea and Vomiting

Start: 2018-10-30End: 2021-02-11Updated: 2023-11-13

Phase 3

A Study of the Safety and Efficacy of Aprepitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) in Pediatric Participants (MK-0869-208)

CompletedNCT01362530

Merck Sharp & Dohme LLCChemotherapy Induced Nausea and Vomiting

Start: 2011-09-13End: 2013-08-16Updated: 2018-09-25

Phase 4

Aprepitant and Ondansetron Monotherapy or Combination for Postoperative Nausea and Vomiting in Thyroid Cancer

CompletedNCT06697782

The First Affiliated Hospital of Zhengzhou UniversityThyroid Cancer

Start: 2024-07-01End: 2025-01-01Updated: 2025-01-22

Unknown Phase

Influence of Antipruritics on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.

CompletedNCT04399148

Universitaire Ziekenhuizen KU LeuvenPruritus

Start: 2019-06-11End: 2019-09-23Updated: 2020-05-27

Related Papers

Aprepitant for the prevention of chemotherapy‐induced nausea and vomiting in paediatric subjects: An analysis by age group

Pediatric Blood & Cancer2018-06-1210 citations

Randomized, placebo-controlled, phase III study of aprepitant in preventing chemotherapy-induced nausea and vomiting in children: Analysis by age group.

Journal of Clinical Oncology2016-05-201 citations

Aprepitant for the prevention of chemotherapy-induced nausea and vomiting in children: a randomised, double-blind, phase 3 trial.

2015-03-1262 citations

Aprepitant for preventing chemotherapy-induced nausea and vomiting (CINV) in children.

Journal of Clinical Oncology2014-05-20