antitumor drug screening assay

OTHER4 trials

Sponsors

Oncotech, The Cleveland Clinic, OHSU Knight Cancer Institute, University of Washington

Conditions

Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAdult Acute Megakaryoblastic Leukemia (M7)Adult Acute Minimally Differentiated Myeloid Leukemia (M0)Adult Acute Monoblastic Leukemia (M5a)Adult Acute Monocytic Leukemia (M5b)Adult Acute Myeloblastic Leukemia With Maturation (M2)Adult Acute Myeloblastic Leukemia Without Maturation (M1)Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities

Phase 2

Evaluation of Drug Resistance in Patients With Metastatic Breast Cancer

OncotechBreast Cancer

Start: 1997-07-31Target: 100Updated: 2013-12-19

Targeted Therapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia

TerminatedNCT01620216

OHSU Knight Cancer InstituteAcute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, Recurrent Acute Lymphoblastic Leukemia +3

Start: 2012-05-11End: 2017-04-30Updated: 2021-11-04

Unknown Phase

Cerebrospinal Fluid Levels of Erlotinib in Patients Receiving Erlotinib For Stage III Non-Small Cell Lung Cancer

CompletedNCT00305617

The Cleveland ClinicLung Cancer

Start: 2004-01-31Target: 10Updated: 2011-05-17

Treatment for Relapsed/Refractory AML Based on a High Throughput Drug Sensitivity Assay

CompletedNCT01872819

University of WashingtonAdult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a) +16

Start: 2013-08-02End: 2014-11-17Updated: 2018-07-11

Related Papers

Precision Medicine Assays Detect Novel Targetable FLT3 Fusions Amenable to Therapeutic Intervention in a Patient with Refractory Acute Myeloid Leukemia

Blood2016-12-02

A Phase II Pilot Study of Kinase Inhibition in Relapsed/Refractory Acute Leukemias: Using an in Vitro Kinase Inhibitor Panel to Select Individualized, Targeted Therapies

Blood2016-12-02

Feasibility Trial of Individualized Therapy for Relapsed or Refractory Acute Myeloid Leukemia Based on a High Throughput in Vitro Drug Sensitivity Assay

Blood2014-12-061 citations

Personalized Approach To Treatment of Acute Myeloid Leukemia Using a High-Throughput Chemosensitivity Assay

Blood2013-11-153 citations