Anti-Thymocyte Globulin (Rabbit)
Sponsors
National Heart, Lung, and Blood Institute (NHLBI), University of Nebraska, St. Jude Children's Research Hospital, McMaster University, National Institute of Allergy and Infectious Diseases (NIAID)
Conditions
Acute LeukemiaAcute Lymphoblastic Leukemia (ALL)Acute Myelogenous Leukemia (AML)Acute Myeloid Leukemia (AML)Aplastic AnemiaBone Marrow Failure SyndromeBone Marrow TransplantChronic Graft-versus-host-disease
Phase 1
Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infusions for Severe Combined Immunodeficiency (SCID)
Active, not recruitingNCT03597594
Start: 2021-09-02End: 2028-07-01Updated: 2025-07-01
Stem Cell Transplantation in Crohn's Disease
RecruitingNCT04224558
Start: 2019-11-15End: 2027-09-30Target: 15Updated: 2026-02-20
CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma
RecruitingNCT07257419
Start: 2026-03-03End: 2035-12-01Target: 60Updated: 2026-03-10
Phase 2
Three Immunosuppressive Treatment Regimens for Severe Aplastic Anemia
CompletedNCT00260689
Start: 2005-11-28End: 2016-05-04Updated: 2017-06-08
Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies
CompletedNCT00566696
Start: 2007-12-14End: 2020-02-06Updated: 2020-04-14
Optimization of NULOJIX® Usage Towards Minimizing CNI Exposure in Simultaneous Pancreas and Kidney Transplantation
TerminatedNCT01790594
Start: 2013-02-28End: 2016-08-31Updated: 2021-07-20
Targeting the IPA and Matching for the Non-Inherited Maternal Antigen for Haplo-Cord Transplantation
Active, not recruitingNCT01810588
Start: 2012-10-16End: 2028-04-30Updated: 2025-09-02
Open-Label Phase 2 Trial of a Steroid-Free, CNI-Free, Belatacept-Based Immunosuppressive Regimen
TerminatedNCT01856257
Start: 2013-07-31End: 2016-04-30Updated: 2020-12-17
Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation
Active, not recruitingNCT02790515
Start: 2016-07-14End: 2026-07-01Updated: 2025-08-12
A Study of the Effect of Blood Stem Cell Transplant After Chemotherapy Alone in Patients With Fanconi Anemia
TerminatedNCT03600909
Start: 2018-05-15End: 2021-04-09Updated: 2022-04-12
ATG Plus PTCy vs ATG for CGVHD Prophylaxis
Active, not recruitingNCT04202835
Start: 2020-10-14End: 2026-02-07Target: 80Updated: 2025-05-11
Tocilizumab for the Prevention of Graft Failure and GVHD in Haplo-Cord Transplantation
Active, not recruitingNCT04395222
Start: 2020-10-07End: 2027-06-30Updated: 2026-01-06
Haploidentical HCT for Severe Aplastic Anemia
RecruitingNCT04558736
Start: 2021-01-21End: 2030-07-01Target: 21Updated: 2025-07-04