ANTI-HUMAN T-LYMPHOCYTE IMMUNOGLOBULIN FROM RABBITS

DRUG4 trials

Sponsors

Hansa Biopharma AB, Centre Hospitalier Universitaire De Nantes, St. Anna Childrens Cancer Research Institute GmbH, Fondazione Italiana Sclerosi Multipla Ente Del Terzo Settore/et S

Conditions

Acute Lymphoblastic LeukaemiaAdults patients will be included in the hematology departments. Eligible patients will be those scheduled to receive an allo-HSC after a RIC conditioning regimen for a myeloid or lymphoid hematological malignancy with a family or non-family HLA-matched donor 10/10Highly sensitised paediatric patients with a positive crossmatch against a living or deceased donor kidney.Relapsing Remitting Multiple Sclerosis

Phase 2

A single-arm, multi-centre trial to evaluate efficacy and safety of imlifidase in highly sensitised children (1-17 years) receiving a kidney transplant with positive crossmatch against a living or deceased donor converted to negative after imlifidase treatment

RecruitingCTIS2022-500230-28-00

Hansa Biopharma ABHighly sensitised paediatric patients with a positive crossmatch against a living or deceased donor kidney.

Start: 2023-06-02Target: 8Updated: 2025-12-22

Randomized Phase 2 study testing two conditioning regimen with a single prophylaxis of graft-versus-host disease by cyclophosphamide and methotrexate post-transplant in patients eligible for matched-donor allograft transplantation _ CY-MET-RIC

RecruitingCTIS2023-509042-35-01

Centre Hospitalier Universitaire De NantesAdults patients will be included in the hematology departments. Eligible patients will be those scheduled to receive an allo-HSC after a RIC conditioning regimen for a myeloid or lymphoid hematological malignancy with a family or non-family HLA-matched donor 10/10

Start: 2024-07-18Target: 82Updated: 2025-06-19

ALL SCTped 2012 FORUM - Allogeneic Stem Cell Transplantation in Children and Adolescents with Acute Lymphoblastic Leukaemia

RecruitingCTIS2024-512657-24-00

St. Anna Childrens Cancer Research Institute GmbHAcute Lymphoblastic Leukaemia

Start: 2014-03-27Target: 1108Updated: 2025-11-18

NO EVIDENCE OF DISEASE ACTIVITY AFTER AUTOLOGOUS HAEMATOPOIETIC STEM CELL TRANSPLANTATION IN AGGRESSIVE MULTIPLE SCLEROSIS: THE NET-MS STUDY

RecruitingCTIS2024-515470-26-00

Fondazione Italiana Sclerosi Multipla Ente Del Terzo Settore/et SRelapsing Remitting Multiple Sclerosis

Start: 2024-10-31Target: 90Updated: 2025-11-17