anti-CEA CAR-T cells

BIOLOGICAL5 trials

Conditions

Breast CancerCarcinoembryonic AntigenColorectal CancerGastric CancerLiver MetastasesMalignant Tumor of Pancreas Metastatic to LiverMetastatic Liver CancerPancreas Cancer

Phase 1

CAR-T Hepatic Artery Infusions and Sir-Spheres for Liver Metastases

CompletedNCT02416466

Roger Williams Medical CenterLiver Metastases

Start: 2015-04-30End: 2018-06-30Updated: 2019-03-26

CAR-T Hepatic Artery Infusions or Pancreatic Venous Infusions for CEA-Expressing Liver Metastases or Pancreas Cancer

CompletedNCT02850536

Roger Williams Medical CenterLiver Metastases

Start: 2017-02-01End: 2021-09-17Updated: 2021-10-21

CAR-T Intraperitoneal Infusions for CEA-Expressing Adenocarcinoma Peritoneal Metastases or Malignant Ascites (IPC)

WithdrawnNCT03682744

Sorrento Therapeutics, Inc.Breast Cancer, Carcinoembryonic Antigen, Colorectal Cancer +4

Start: 2018-09-13End: 2021-03-31Updated: 2022-04-06

Anti-CEA CAR-T Cells to Treat Colorectal Liver Metastases

RecruitingNCT05240950

Changhai HospitalColorectal Cancer, Metastatic Liver Cancer

Start: 2022-08-25End: 2026-12-25Target: 18Updated: 2022-03-11

Phase 2

Study of Anti-CEA CAR-T + Chemotherapy VS Chemotherapy Alone in Patients With CEA+Pancreatic Cancer & Liver Metastases

WithdrawnNCT04037241

Sorrento Therapeutics, Inc.Malignant Tumor of Pancreas Metastatic to Liver

Start: 2021-11-01End: 2022-01-01Updated: 2022-04-01

Journal of Clinical Oncology2025-05-282 citations

Global Perspective on the Development of Genetically Modified Immune Cells for Cancer Therapy.

2021-02-156 citations

HITM-SURE: Hepatic immunotherapy for metastases phase Ib anti-CEA CAR-T study utilizing pressure enabled drug delivery

Journal for ImmunoTherapy of Cancer2020-08-0172 citations

Abstract CT109: HITM-SIR: Phase Ib trial of CAR-T hepatic artery infusions and selective internal radiation therapy for liver metastases

Cancer Research2017-07-017 citations

anti-CEA CAR-T cells

Sponsors

Conditions

Phase 1

Phase 2

Related Papers