Anamorelin Hydrochloride

DRUG5 trials

Conditions

Advanced Malignant Solid NeoplasmAnorexiaC-Reactive Protein MeasurementCachexia; CancerCancer FatigueLung Non-Small Cell CarcinomaMetastatic Malignant Solid NeoplasmMetastatic Pancreatic Cancer

Phase 1

Effect of a Ghrelin Receptor Agonist on Muscle and Bone

CompletedNCT04021706

Tufts UniversityOsteopenia, Sarcopenia

Start: 2019-12-05End: 2023-01-26Updated: 2024-03-27

Phase 2

Anamorelin Hydrochloride, Physical Activity, and Nutritional Counseling in Decreasing Cancer-Related Fatigue in Patients With Incurable Metastatic or Recurrent Solid Tumors

Active, not recruitingNCT03035409

M.D. Anderson Cancer CenterAdvanced Malignant Solid Neoplasm, Cancer Fatigue, C-Reactive Protein Measurement +3

Start: 2017-02-08End: 2028-02-28Updated: 2026-06-18

Anamorelin Hydrochloride in Reducing Anorexia in Patients With Advanced Non-small Cell Lung Cancer

Active, not recruitingNCT03637816

M.D. Anderson Cancer CenterAnorexia, Lung Non-Small Cell Carcinoma, Stage IIIA Lung Cancer AJCC v8 +6

Start: 2018-11-27End: 2026-12-31Updated: 2026-04-15

Anamorelin Study for Advanced Pancreatic Cancer

TerminatedNCT04844970

Lahey ClinicMetastatic Pancreatic Cancer

Start: 2023-04-01End: 2023-11-07Updated: 2025-11-17

Phase 3

A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)

CompletedNCT03743051

Helsinn Healthcare SACachexia; Cancer, Non Small Cell Lung Cancer

Start: 2019-03-05End: 2023-02-11Updated: 2024-06-26

Related Papers

Perception of subjective lived experiences of individuals with anorexia-cachexia in patients with advanced lung cancer.

2023-10-104 citations

Phase II, double blind, placebo controlled, multi-site study to evaluate the safety, feasibility and desirability of conducting a phase III study of anamorelin for anorexia in people with small cell lung cancer: A study protocol (LUANA trial)

PLoS ONE2023-05-174 citations

Anamorelin combined with physical activity, and nutritional counseling for cancer-related fatigue: a preliminary study.

2021-07-3116 citations