amsacrine

DRUG10 trials

Conditions

Acute myeloid leukemiaChronic Myelomonocytic LeukemiaLeukemiaMyelodysplastic SyndromesNeutropeniaPatients with myelodysplastic syndrome (MDS)Relapsed or Refractory Acute Myeloid LeukemiaSecondary Acute Myeloid Leukemia

Phase 1

Laromustine, Daunorubicin, and Cytarabine in Treating Patients With Acute Myeloid Leukemia

CompletedNCT00840684

Institut Paoli-CalmettesLeukemia

Start: 2009-01-31Target: 135Updated: 2011-05-13

Venetoclax in Addition to Sequential Conditioning With Fludarabine / Amsacrine / Ara-C (FLAMSA) + Treosulfan for Allogeneic Blood Stem Cell Transplantation in Patients With MDS, CMML or sAML

RecruitingNCT05807932

Heinrich-Heine University, DuesseldorfChronic Myelomonocytic Leukemia, Myelodysplastic Syndromes, Secondary Acute Myeloid Leukemia

Start: 2023-06-26End: 2028-01-30Target: 38Updated: 2024-05-01

Phase-I/II trial to assess the safety and efficacy of Venetoclax in addition to sequential conditioning with Fludarabine / Amsacrine / Ara-C (FLAMSA) + Treosulfan for allogeneic blood stem cell transplantation in patients with MDS, CMML or sAML

RecruitingCTIS2024-514688-24-00

Heinrich-Heine-Universitaet Duesseldorfchronic myelomonocytic leukemia (CMML) or secondary acute myeloid leukemia (sAML) before stem cell transplantation, Patients with myelodysplastic syndrome (MDS)

Start: 2023-05-26Target: 38Updated: 2025-10-09

Phase 2

Clofarabine or High-Dose Cytarabine and Pegaspargase in Children with ALL

CompletedNCT01228331

Universitätsklinikum Hamburg-EppendorfLeukemia

Start: 2010-10-31End: 2024-11-20Updated: 2024-12-11

Phase 3

Combination Chemotherapy, Biological Therapy, and Bone Marrow Transplantation in Treating Patients With Acute Myeloid Leukemia

NCT00002658

Medical Research CouncilLeukemia, Neutropenia

Start: 1994-01-31Target: 2000Updated: 2013-12-19

Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myeloid Leukemia

CompletedNCT00003436

Medical Research CouncilLeukemia, Myelodysplastic Syndromes

Start: 1998-07-31End: 2005-12-31Target: 2000Updated: 2013-12-04

Combination Chemotherapy With or Without G-CSF in Treating Older Patients With Acute Myeloid Leukemia

CompletedNCT00002719

European Organisation for Research and Treatment of Cancer - EORTCLeukemia, Neutropenia

Start: 1995-12-31Target: 500Updated: 2012-07-02

A Randomized Phase III Study of Intensive Consolidation With High Dose Cytosine Arabinoside in Acute Myelogenous Leukemia (AML-8B)

CompletedNCT01324063

European Organisation for Research and Treatment of Cancer - EORTCLeukemia

Start: 1986-11-30Target: 160Updated: 2012-07-16

Dexamethasone in Refractory or First Relapsed Acute Myeloid Leukemia

TerminatedNCT03765541

University Hospital, ToulouseRelapsed or Refractory Acute Myeloid Leukemia

Start: 2020-01-13End: 2024-05-31Updated: 2025-04-10

IMPACT-AML: A RANDOMIZED PRAGMATIC CLINICAL TRIAL FOR RELAPSE OR REFRACTORY ACUTE MYELOID LEUKEMIA

RecruitingCTIS2024-514517-35-00

Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori IRST S.r.l.Acute myeloid leukemia

Start: 2025-02-27Target: 267Updated: 2025-12-18

Related Papers

Clofarabine increases the eradication of minimal residual disease of primary B-precursor acute lymphoblastic leukemia compared to high-dose cytarabine without improvement of outcome. Results from the randomized clinical trial 08-09 of the Cooperative Acute Lymphoblastic Leukemia Study Group.