Amodiaquine

DRUG18 trials

Conditions

Drug CombinationHIV InfectionsHealthyIntegrated ControlMalariaMalaria, FalciparumMalaria,FalciparumMass Drug Administration With Anthelminthic Drugs

Phase 1

A Comparative Safety and Activity Study With Ferroquine Associated With Artesunate Versus Amodiaquine Associated With Artesunate in African Adult Patients With Uncomplicated Malaria

CompletedNCT00563914

SanofiMalaria

Start: 2007-10-31End: 2008-11-30Updated: 2009-12-21

Study of Artemether-lumefantrine, Amodiaquine and Primaquine in Healthy Subjects

TerminatedNCT02696954

University of OxfordDrug Combination, Healthy, Pharmacokinetic

Start: 2016-11-18End: 2019-03-31Updated: 2019-06-28

Pharmacokinetic Study of Artemether-lumefantrine and Amodiaquine in Healthy Subjects

TerminatedNCT04080895

University of OxfordDrug Combination, Healthy, Pharmacokinetic

Start: 2022-11-01End: 2025-04-01Updated: 2026-01-12

Phase 2

Efficacy of Amodiaquine in the Treatment of Uncomplicated Falciparum Malaria in Young Children of Burkina Faso

CompletedNCT00261222

Heidelberg UniversityMalaria

Start: 2005-09-30End: 2005-11-30Target: 120Updated: 2010-02-03

Long-Term Follow-up of Children for a 2-Year Period to Confirm the Safety and Immunogenicity of GSK 257049 Vaccine

CompletedNCT00323622

GlaxoSmithKlineMalaria

Start: 2005-04-30End: 2007-05-31Updated: 2016-12-09

Safety and Efficacy of Methylene Blue Combined With Artesunate or Amodiaquine for Malaria Treatment in Children of Burkina Faso: a Pilot Study

CompletedNCT00354380

Heidelberg UniversityMalaria

Start: 2006-09-30End: 2006-11-30Updated: 2006-10-24

Evaluation of Oral Activated Charcoal on Antimalarial Drug's Ability to Kill Parasites in Malian Children With Malaria

CompletedNCT01955382

National Institute of Allergy and Infectious Diseases (NIAID)Malaria, Severe Malaria

Start: 2013-09-30End: 2015-07-31Updated: 2018-02-06

Phase 2 Efficacy Study of Primaquine and Methylene Blue

CompletedNCT02831023

University of California, San FranciscoMalaria

Start: 2016-07-31End: 2017-01-31Updated: 2017-01-11

Gametocytocidal and Transmission-blocking Efficacy of ASAQ and ALAQ With or Without PQ in Mali

CompletedNCT05550909

London School of Hygiene and Tropical MedicineMalaria,Falciparum

Start: 2022-10-17End: 2023-01-26Updated: 2024-10-01

Phase 3

Efficacy and Safety of Sulphadoxine-pyrimethamine and Amodiaquine in Ghanaian Pregnant Women

CompletedNCT00131703

London School of Hygiene and Tropical MedicineMalaria, Pregnancy

Start: 2003-03-31End: 2005-03-31Target: 900Updated: 2025-03-04

A Trial of Four Drug Regimens for the Prevention of Malaria in Senegalese Children

CompletedNCT00132548

London School of Hygiene and Tropical MedicineMalaria

Start: 2004-06-30End: 2004-12-31Target: 2200Updated: 2017-01-12

Effectiveness, Feasibility and Acceptability of Seasonal Malaria Chemoprevention in Aweil South County in South Sudan

NCT05471544

Malaria ConsortiumMalaria

Start: 2022-07-18End: 2024-12-31Target: 3575Updated: 2024-03-25

Phase 4

Chloroquine and Amodiaquine for Treatment of Malaria in Children

CompletedNCT00137514

Bandim Health ProjectMalaria, Falciparum

Start: 2001-03-31End: 2004-05-31Target: 720Updated: 2008-04-08

Arsucam® (Artesunate + Amiodaquine) Efficacy and TOLerance

CompletedNCT00445796

SanofiMalaria

Start: 2005-06-30Target: 300Updated: 2008-04-10

Chemoprevention Efficacy Study in Burkina Faso

NCT05478954

Malaria ConsortiumMalaria

Start: 2022-07-15End: 2023-12-01Updated: 2023-11-01

Unknown Phase

Antimalarial Drug Resistance in Mali

CompletedNCT00127998

Centers for Disease Control and PreventionMalaria

Start: 2005-07-31Target: 1011Updated: 2006-08-16

Relationship Between HIV and Malaria in Ugandan Children

CompletedNCT00356824

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Malaria

Start: 2005-11-30End: 2010-05-31Target: 300Updated: 2021-11-01

Feasibility and Safety of Combining Anti-malarial With Deworming Drugs in African Children

NCT05354258

London School of Hygiene and Tropical MedicineIntegrated Control, Malaria, Mass Drug Administration With Anthelminthic Drugs +3

Start: 2022-06-16End: 2023-09-30Target: 600Updated: 2022-07-14

2024-12-177 citations

Feasibility and safety of integrating mass drug administration for helminth control with seasonal malaria chemoprevention among Senegalese children: a randomized controlled, observer-blind trial

Malaria Journal2023-11-131 citations

Safety and effectiveness of delivering mass drug administration for helminths through the seasonal malaria chemoprevention platform among Senegalese children: study protocol for a randomised controlled trial.

2022-08-037 citations

A randomized feasibility trial comparing four antimalarial drug regimens to induce Plasmodium falciparum gametocytemia in the controlled human malaria infection model

eLife2018-02-2667 citations

Efficacy and safety of primaquine and methylene blue for prevention of Plasmodium falciparum transmission in Mali: a phase 2, single-blind, randomised controlled trial.

2018-02-0681 citations

Phase 2a, Open-Label, 4-Escalating-Dose, Randomized Multicenter Study Evaluating the Safety and Activity of Ferroquine (SSR97193) Plus Artesunate, versus Amodiaquine Plus Artesunate, in African Adult Men with Uncomplicated Plasmodium falciparum Malaria

American Journal of Tropical Medicine and Hygiene2017-08-0229 citations

Temporal and Seasonal Changes of Genetic Polymorphisms Associated with Altered Drug Susceptibility to Chloroquine, Lumefantrine, and Quinine in Guinea-Bissau between 2003 and 2012

Antimicrobial Agents and Chemotherapy2014-11-2514 citations

Long-term safety and efficacy of the RTS,S/AS02A malaria vaccine in Mozambican children.

2009-08-0181 citations

Strong gametocytocidal effect of methylene blue-based combination therapy against falciparum malaria: a randomised controlled trial.

2009-05-0589 citations

Safety and efficacy of methylene blue combined with artesunate or amodiaquine for uncomplicated falciparum malaria: a randomized controlled trial from Burkina Faso.

2008-02-2066 citations