AMG 732
Sponsors
Amgen Inc., Amgen
Conditions
Thyroid Eye Disease
Phase 1
A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease
Active, not recruitingNCT06401044
Start: 2024-05-30End: 2027-12-24Updated: 2026-08-10
A Phase 1/2, Randomized, Double-Masked, Placebo-Controlled, Multicenter Study to Assess the Safety, Pharmacokinetics, and Efficacy of AMG 732 in Healthy Subjects and Subjects with Moderate-to-Severe Active Thyroid Eye Disease
RecruitingCTIS2024-514110-12-00
Start: 2025-10-22Target: 19Updated: 2025-12-11
Phase 2
An Open-label, Rollover Trial to Evaluate the Efficacy and Safety of AMG 732 in Participants With Thyroid Eye Disease
RecruitingNCT07438405
Start: 2026-05-07End: 2028-07-14Target: 30Updated: 2026-07-23
An Open-Label, Rollover Study for Participants With Thyroid Eye Disease Previously Enrolled in Amgen-Sponsored AMG 732 Studies and are Primary Proptosis Non-responders or who Relapsed During the Safety Follow-up
Not yet recruitingCTIS2025-523280-38-00
Target: 2Updated: 2026-05-20