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AMG 655

DRUG7 trials

Sponsors

Amgen, NantCell, Inc.

Conditions

Adenocarcinoma of the PancreasColon CancerColorectal CancerDiffuse Large Cell LymphomaHodgkin's LymphomaLocally AdvancedLocally Advanced or Metastatic, Unresectable Soft Tissue SarcomaLow Grade Lymphoma

Phase 1

A Phase 1b/2 Study of AMG 655 in Combination With Paclitaxel and Carboplatin for the First-Line Treatment of Advanced Non-Small Cell Lung Cancer
CompletedNCT00534027
AmgenNon-Small Cell Lung Cancer
Start: 2008-01-31End: 2011-03-31Updated: 2016-01-14
Phase 1b/2 Study of AMG 655 With mFOLFOX6 and Bevacizumab for First-Line Metastatic Colorectal Cancer
CompletedNCT00625651
AmgenColon Cancer, Colorectal Cancer, Metastatic Colorectal Cancer +1
Start: 2007-10-31End: 2011-09-30Updated: 2014-04-25
Phase 1b/2 Study of AMG 655 With Doxorubicin for the First-Line Treatment of Unresectable Soft Tissue Sarcoma
CompletedNCT00626704
AmgenLocally Advanced or Metastatic, Unresectable Soft Tissue Sarcoma, Sarcoma, Soft Tissue Sarcoma
Start: 2007-11-30End: 2011-03-31Updated: 2015-05-25
QUILT-2.019: A Study of AMG 655 or AMG 479 in Combination With Gemcitabine for Treatment of Metastatic Pancreatic Cancer
CompletedNCT00630552
NantCell, Inc.Adenocarcinoma of the Pancreas, Metastatic Pancreatic Cancer, Pancreatic Cancer
Start: 2007-06-30End: 2012-04-30Updated: 2024-10-17
Phase 1b Lymphoma Study of AMG 655 in Combination With Bortezomib or Vorinostat
CompletedNCT00791011
AmgenDiffuse Large Cell Lymphoma, Hodgkin's Lymphoma, Low Grade Lymphoma +3
Start: 2008-02-29End: 2011-08-31Updated: 2014-03-05
QUILT-3.026: AMG 655 in Combination With AMG 479 in Advanced, Refractory Solid Tumors
TerminatedNCT00819169
NantCell, Inc.Colorectal Cancer, Locally Advanced, Metastatic Cancer +5
Start: 2009-01-16End: 2011-08-10Updated: 2024-08-20

Phase 2

QUILT-2.018: Safety & Efficacy of FOLFIRI With AMG 479 or AMG 655 vs FOLFIRI Alone in KRAS-mutant Metastatic Colorectal Carcinoma
CompletedNCT00813605
NantCell, Inc.Metastatic Colorectal Cancer
Start: 2009-03-31End: 2012-06-30Updated: 2016-10-27

Related Papers

A randomized phase 2 study of paclitaxel and carboplatin with or without conatumumab for first-line treatment of advanced non-small-cell lung cancer.
2013-03-0162 citations