Amcenestrant
Sponsors
QuantumLeap Healthcare Collaborative, Sanofi
Conditions
AngiosarcomaBreast CancerBreast Cancer MetastaticBreast NeoplasmsBreast TumorsEarly-stage Breast CancerHER2-negative Breast CancerHER2-positive Breast Cancer
Phase 1
Phase 1/2 Study of Amcenestrant (SAR439859) Single Agent and in Combination With Other Anti-cancer Therapies in Postmenopausal Women With Estrogen Receptor Positive Advanced Breast Cancer
TerminatedNCT03284957
Start: 2017-09-20End: 2024-11-08Updated: 2025-11-24
Study to Determine Absorption, Metabolism, and Excretion of [14C]-SAR439859, and to Assess Absolute Oral Bioavailability of Amcenestrant (SAR439859), in Healthy Post-menopausal Women
CompletedNCT04940026
Start: 2021-06-15End: 2021-08-19Updated: 2025-09-24
Pharmacokinetics of Amcenestrant in Female Hepatic Impaired Participants as Compared to Participants With Normal Hepatic Function
TerminatedNCT05126329
Start: 2021-11-15End: 2022-05-16Updated: 2025-09-22
Phase 2
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
RecruitingNCT01042379
Start: 2010-03-01End: 2031-12-01Target: 5000Updated: 2026-03-13
Phase 2 Study of Amcenestrant (SAR439859) Versus Physician's Choice in Locally Advanced or Metastatic ER-positive Breast Cancer
TerminatedNCT04059484
Start: 2019-10-22End: 2025-01-02Updated: 2026-02-24
Phase 3
Related Papers
93 more papers not shown