Ambroxol
Sponsors
Helse Fonna HF, Amsterdam UMC Stichting, Universitair Medisch Centrum Groningen, Boehringer Ingelheim, Exsar Corporation
Conditions
Amyotrophic Lateral SclerosisDementia With Lewy BodiesDementia with Lewy BodiesGaucher Disease, Type 1Gaucher Disease, Type 3Gaucher disease type 3HealthyParkinson Disease
Phase 1
Phase 2
Ambroxol as a Treatment for Parkinson's Disease Dementia
Active, not recruitingNCT02914366
Start: 2015-11-30End: 2025-12-31Updated: 2024-02-28
Ambroxol in Disease Modification in Parkinson Disease
CompletedNCT02941822
Start: 2016-12-31End: 2018-05-31Updated: 2020-04-15
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy
CompletedNCT03950050
Start: 2019-03-01End: 2022-12-30Updated: 2023-02-14
Ambroxol in New and Early DLB, A Phase IIa Multicentre Randomized Controlled Double Blind Clinical Trial
NCT04588285
Start: 2021-05-04End: 2025-07-01Target: 180Updated: 2023-12-21
A Double-blind Randomised, Placebo-controlled Clinical Trial to Test Ambroxol Treatment in ALS
NCT05959850
Start: 2023-06-13End: 2024-12-31Target: 50Updated: 2023-09-07
GREAT; GRoningen Early-PD Ambroxol Treatment Trial
Not yet recruitingCTIS2024-514976-41-00
Target: 80Updated: 2024-09-23
A phase IIa multicentre randomized controlled double blind clinical trial to demonstrate clinical efficacy on cognitive, neuropsychiatric and functional outcomes of Ambroxol in New and Early patients with prodromal and mild Dementia with Lewybodies (The ANeED study)
RecruitingCTIS2024-510720-38-00
Start: 2021-01-12Target: 156Updated: 2024-10-22
Phase 3
Double-blind Trial to Investigate Efficacy and Tolerance of Ambroxol Lozenges 20 mg in Sore Throat
CompletedNCT00525044
Start: 2007-08-01End: 2008-01-01Updated: 2019-07-11
Effectiveness of ambroxol in children and adults with Gaucher disease 3: n-of-1 series
Not yet recruitingCTIS2024-514012-28-00
Target: 4Updated: 2024-11-25