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Ambroxol

DRUG12 trials

Sponsors

Helse Fonna HF, Amsterdam UMC Stichting, Universitair Medisch Centrum Groningen, Boehringer Ingelheim, Exsar Corporation

Conditions

Amyotrophic Lateral SclerosisDementia With Lewy BodiesDementia with Lewy BodiesGaucher Disease, Type 1Gaucher Disease, Type 3Gaucher disease type 3HealthyParkinson Disease

Phase 1

Phase 2

Ambroxol as a Treatment for Parkinson's Disease Dementia
Active, not recruitingNCT02914366
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sParkinson's Disease Dementia
Start: 2015-11-30End: 2025-12-31Updated: 2024-02-28
Ambroxol in Disease Modification in Parkinson Disease
CompletedNCT02941822
University College, LondonParkinson Disease
Start: 2016-12-31End: 2018-05-31Updated: 2020-04-15
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy
CompletedNCT03950050
Shaare Zedek Medical CenterGaucher Disease, Type 1
Start: 2019-03-01End: 2022-12-30Updated: 2023-02-14
Ambroxol in New and Early DLB, A Phase IIa Multicentre Randomized Controlled Double Blind Clinical Trial
NCT04588285
Helse FonnaDementia With Lewy Bodies
Start: 2021-05-04End: 2025-07-01Target: 180Updated: 2023-12-21
A Double-blind Randomised, Placebo-controlled Clinical Trial to Test Ambroxol Treatment in ALS
NCT05959850
The Florey Institute of Neuroscience and Mental HealthAmyotrophic Lateral Sclerosis
Start: 2023-06-13End: 2024-12-31Target: 50Updated: 2023-09-07
GREAT; GRoningen Early-PD Ambroxol Treatment Trial
Not yet recruitingCTIS2024-514976-41-00
Universitair Medisch Centrum GroningenParkinson's disease
Target: 80Updated: 2024-09-23
A phase IIa multicentre randomized controlled double blind clinical trial to demonstrate clinical efficacy on cognitive, neuropsychiatric and functional outcomes of Ambroxol in New and Early patients with prodromal and mild Dementia with Lewybodies (The ANeED study)
RecruitingCTIS2024-510720-38-00
Helse Fonna HFDementia with Lewy Bodies
Start: 2021-01-12Target: 156Updated: 2024-10-22

Phase 3

Unknown Phase

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