ALPN-101

DRUG3 trials

Sponsors

Alpine Immune Sciences, Inc., Alpine Immune Sciences Inc, A Subsidiary of Vertex

Conditions

Graft Vs Host DiseaseHealthy VolunteersSystemic Lupus Erythematosus

Phase 1

Adult Healthy Volunteers Study to Evaluate ALPN-101 Safety

CompletedNCT03748836

Alpine Immune Sciences, Inc.Healthy Volunteers

Start: 2019-01-29End: 2019-11-18Updated: 2019-12-05

ALPN-101 in Steroid-resistant or Steroid-refractory Acute GVHD

TerminatedNCT04227938

Alpine Immune Sciences, Inc.Graft Vs Host Disease

Start: 2020-05-11End: 2020-05-21Updated: 2023-08-28

Phase 2

ALPN-101 (Acazicolcept) in Systemic Lupus Erythematosus

CompletedNCT04835441

Alpine Immune Sciences Inc, A Subsidiary of VertexSystemic Lupus Erythematosus

Start: 2021-06-22End: 2024-07-09Updated: 2025-08-15