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Allogeneic MSC
BIOLOGICAL
3 trials
Sponsors
University of Illinois at Chicago
, Leiden University Medical Center
, Longeveron Inc.
Conditions
Cornea
Corneal Defect
Mesenchymal Stromal Cells
Mild Alzheimer's Disease
Pulmonary Emphysema
Safety
Phase 1
Safety of Locally Delivered Allogeneic Mesenchymal Stromal Cells
Completed
NCT04626583
University of Illinois at Chicago
Cornea, Corneal Defect, Mesenchymal Stromal Cells +1
Start: 2021-03-05
End: 2023-04-21
Updated: 2024-12-16
Phase 2
Allogeneic MSC Treatment for Pulmonary Emphysema
NCT04918706
Leiden University Medical Center
Mesenchymal Stromal Cells, Pulmonary Emphysema
Start: 2019-06-25
End: 2022-06-01
Target: 30
Updated: 2021-06-09
Lomecel-B Effects on Alzheimer's Disease
Completed
NCT05233774
Longeveron Inc.
Mild Alzheimer's Disease
Start: 2021-12-28
End: 2023-09-29
Updated: 2024-02-20
Related Papers
Allogeneic mesenchymal stem cell therapy with laromestrocel in mild Alzheimer’s disease: a randomized controlled phase 2a trial
Nature Medicine
2025-03-10
23 citations
Results from a Phase 2a Proof‐of‐Concept Double‐Blind, Randomized, Placebo‐Controlled Trial of Lomecel‐B<sup>TM</sup> in Mild Alzheimer’s Disease Dementia
Alzheimer s & Dementia
2024-12-01
1 citations
Reduction in Alzheimer’s disease brain atrophy by MRI measures in a phase 2a clinical trial of Lomecel‐B<sup>TM</sup>
Alzheimer s & Dementia
2024-12-01
High-Dimensional Mass Cytometry Reveals Emphysema-associated Changes in the Pulmonary Immune System
American Journal of Respiratory and Critical Care Medicine
2024-03-27
11 citations