albumin 20%

DRUG4 trials

Sponsors

Instituto Grifols, S.A., Sodertalje Hospital, Insel Gruppe AG, University Hospital Bern, Joachim Zdolsek

Conditions

Alzheimer's DiseaseBenign NeoplasmBlood Loss, SurgicalColorectal CancerColorectal DisordersFluid RetentionGynecologic CancerInflammation

Phase 2

A Study to Evaluate Albumin and Immunoglobulin in Alzheimer's Disease

CompletedNCT01561053

Instituto Grifols, S.A.Alzheimer's Disease

Start: 2012-04-19End: 2018-03-06Updated: 2019-07-31

Phase 4

Volume Kinetics for 20% Albumin in Different Clinical Situations

Sodertalje HospitalInflammation, Unconscious

Start: 2016-02-29End: 2019-04-01Target: 45Updated: 2018-03-20

Impact of Hyperoncotic Albumin to Support Blood Loss Replacement

CompletedNCT03848507

Insel Gruppe AG, University Hospital BernBlood Loss, Surgical, Fluid Retention

Start: 2019-03-18End: 2020-02-18Updated: 2020-02-20

Fluid Challenge and Plasma Volume, During Surgery

RecruitingNCT05726136

Joachim ZdolsekBenign Neoplasm, Colorectal Cancer, Colorectal Disorders +2

Start: 2023-10-23End: 2025-10-31Target: 60Updated: 2024-03-18

Related Papers

Post-Hoc Assessment of Cognitive Efficacy in Alzheimer’s Disease Using a Latent Growth Mixture Model in AMBAR, a Phase 2B Randomized Controlled Trial

Current Alzheimer Research2024-05-01

Application of a Novel Endpoint Staging Framework: Proof of Concept in the AMBAR Study

Journal of Alzheimer s Disease2024-03-13

Neuroimaging analyses from a randomized, controlled study to evaluate plasma exchange with albumin replacement in mild-to-moderate Alzheimer’s disease: additional results from the AMBAR study

European Journal of Nuclear Medicine and Molecular Imaging2022-07-2211 citations

Can perioperative hemodilution be monitored with non-invasive measurement of blood hemoglobin?

2021-05-061 citations

Albumin glycation in Alzheimer’s disease patients: Results from the AMBAR trial

Alzheimer s & Dementia2020-12-011 citations

Association between recipient survival and blood donor age after blood transfusion in a surgery intensive care unit: a multicenter randomized controlled trial study protocol.

2020-07-081 citations

P3‐177: RELATIONSHIP OF ALBUMIN GLYCATION WITH Aβ<sub>42</sub> AND TAU BIOMARKERS IN CSF FROM ALZHEIMER'S DISEASE PATIENTS AND HEALTHY CONTROLS

Alzheimer s & Dementia2019-07-01

P3‐240: ALBUMIN OXIDATION IN CSF FROM ALZHEIMER'S DISEASE PATIENTS IS ASSOCIATED WITH ABETA‐42 AND TAU BIOMARKERS AND APOE GENOTYPE

Alzheimer s & Dementia2018-07-01

[P2–257]: ALBUMIN OXIDATION STATUS IN CSF AND PLASMA SAMPLES FROM ALZHEIMER's DISEASE PATIENTS

Alzheimer s & Dementia2017-07-01

P1‐048: Changes in Cognitive Status of Alzheimer’s Disease Patients Treated with Plasma Exchange and Replacement with Human Albumin Plus Immunoglobulin: Interim Global Results of the Ambar Trial

Alzheimer s & Dementia2016-07-011 citations

P2‐067: Modifications in Albumin Molecular Profile in a Phase 2 Study Based on Therapeutic Plasma Exchange and 5% Albumin Replacement in Alzheimer's Disease

Alzheimer s & Dementia2016-07-01