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AL-335

DRUG9 trials

Sponsors

Alios Biopharma Inc., Janssen Research & Development, LLC, Janssen Pharmaceutical K.K.

Conditions

Chronic Hepatitis CHealthyHepatitis C, ChronicRenal Insufficiency

Phase 1

First in Human Study of AL-335; Single Dose, Food Effect in Healthy Volunteers; Multiple Doses in Chronic Hepatitis C Genotype 1
CompletedNCT02339207
Alios Biopharma Inc.Chronic Hepatitis C
Start: 2014-12-31End: 2016-05-31Updated: 2019-10-16
A Study to Evaluate the Effect of ACH-3102 and Simeprevir on AL-335 Pharmacokinetics in Healthy Volunteers
CompletedNCT02512562
Alios Biopharma Inc.Chronic Hepatitis C
Start: 2015-07-31End: 2015-08-31Updated: 2019-10-16
Study to Investigate the Pharmacokinetics, Safety and Tolerability of Odalasvir and AL-335 in Healthy Japanese Participants
CompletedNCT02821858
Janssen Research & Development, LLCHealthy
Start: 2016-06-14End: 2016-09-30Updated: 2018-03-29
Study to Investigate the Pharmacokinetic Interaction Between 2 Direct Acting Antiviral Agents Odalasvir and AL-335 and Between 3 Direct Acting Antiviral Agents Simeprevir, Odalasvir and AL-335 at Steady State in Healthy Japanese Participants
CompletedNCT02824315
Janssen Research & Development, LLCHealthy
Start: 2016-05-31End: 2016-10-31Updated: 2025-02-03
To Evaluate the Effects of Odalasvir and AL-335 With Simeprevir on the Single-Dose Pharmacokinetics of Ethinylestradiol and Drospirenone in Healthy Female Participants
CompletedNCT02885454
Janssen Research & Development, LLCHealthy
Start: 2016-08-31End: 2016-12-31Updated: 2017-01-23
A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of AL-335
CompletedNCT02894905
Janssen Research & Development, LLCRenal Insufficiency
Start: 2016-09-13End: 2017-08-16Updated: 2017-12-20

Phase 2

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