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Agomelatine

DRUG17 trials

Sponsors

Universitair Medisch Centrum Utrecht, Novartis, National Taiwan University Hospital, Baker Heart and Diabetes Institute, H. Lundbeck A/S

Conditions

Acute Ischemic StrokeAnxiety DisordersDelusional DisorderDementiaDepressionDepressive Disorder, MajorDepressive Disorder, Treatment-ResistantFibromyalgia

Phase 3

Efficacy, Safety and Tolerability of Agomelatine in the Treatment of Major Depressive Disorder
CompletedNCT00411242
NovartisMajor Depressive Disorder (MDD)
Start: 2006-12-31Updated: 2020-12-23
Efficacy, Safety and Tolerability of Agomelatine in the Treatment of Major Depressive Disorder
CompletedNCT00411099
NovartisMajor Depressive Disorder
Start: 2006-12-31Updated: 2020-12-23
A Placebo- and Paroxetine-controlled Study of the Efficacy, Safety and Tolerability of Agomelatine (25 or 50 mg) in the Treatment of Major Depressive Disorder (MDD)
CompletedNCT00463242
NovartisMajor Depressive Disorder
Start: 2007-03-31Updated: 2020-12-23
Efficacy, Safety and Tolerability of Agomelatine in the Prevention of Relapse of Major Depressive Disorder
CompletedNCT00467402
NovartisMajor Depressive Disorder
Start: 2007-04-30Updated: 2020-12-23
A Study of Vortioxetine (Lu AA21004) in Comparison to Agomelatine in Adults Suffering From Major Depression With Inadequate Response to Previous Medication
CompletedNCT01488071
H. Lundbeck A/SMajor Depressive Disorder
Start: 2012-01-31Updated: 2014-03-26
Pharmacovigilance in Gerontopsychiatric Patients
TerminatedNCT02374567
Hannover Medical SchoolAnxiety Disorders, Dementia, Depression +2
Start: 2015-01-31End: 2017-06-28Updated: 2018-02-28
A Study of Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant Depression
WithdrawnNCT03852160
Janssen-Cilag International NVDepressive Disorder, Treatment-Resistant
Start: 2019-12-01End: 2021-07-25Updated: 2025-04-27
A randomised, controlled trial to investigate the effect of a six-week intensified pharmacological treatment for major depressive disorder compared to treatment as usual in subjects who had a first-time treatment failure on their first-line treatment.
RecruitingCTIS2023-506617-21-00
Universitair Medisch Centrum UtrechtMajor depressive disorder
Start: 2024-08-29Target: 360Updated: 2025-04-17

Phase 4

Cardiovascular Effects of Agomelatine and Escitalopram in Patients With Major Depressive Disorder (MDD)
NCT01483053
Baker Heart and Diabetes InstituteMajor Depressive Disorder (MDD)
Start: 2014-01-31End: 2015-02-28Target: 40Updated: 2013-12-18
Agomelatine Treatment of Depression in Schizophrenia (AGOPSYCH)
CompletedNCT01822418
Central Institute of Mental Health, MannheimDelusional Disorder, Schizoaffective Disorder, Schizophrenia
Start: 2013-01-31End: 2015-12-31Updated: 2018-03-08
Comparison of the Efficacy, Safety, and Relapse of ECT to ECT Plus Agomelatine for Depressed Patients
CompletedNCT04181567
Kaohsiung Kai-Suan Psychiatric HospitalMajor Depressive Disorder
Start: 2014-03-03End: 2019-11-22Updated: 2019-11-29
A Double-blind, Placebo-controlled Study of Antidepressant Augmentation With Agomelatine
CompletedNCT04589143
Central South UniversityMajor Depressive Disorder
Start: 2020-10-01End: 2023-01-30Updated: 2024-04-01
Prophylactic Effects of Agomelatine for Poststroke Depression
NCT05426304
First Affiliated Hospital, Sun Yat-Sen UniversityAcute Ischemic Stroke, Depression
Start: 2022-10-01End: 2024-05-31Target: 420Updated: 2022-07-27
A Study on the Efficacy of Agomelatine Combined With Antipsychotics to Treat Negative Symptoms in Schizophrenia
NCT05646264
Shanghai Mental Health CenterNegative Symptoms in Schizophrenia, Schizophrenia
Start: 2023-01-01End: 2023-08-01Target: 220Updated: 2022-12-12
Switching Medication and Augmentation Strategies for SSRI-Resistant Adolescent Depression(SMART-I)
Not yet recruitingNCT07011693
Xinyu ZhouMajor Depressive Disorder (MDD)
Start: 2025-06-20End: 2027-12-31Target: 400Updated: 2025-06-10

Unknown Phase

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