Aggrenox

DRUG4 trials

Sponsors

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Boehringer Ingelheim

Conditions

HealthyKidney FailureStroke

Phase 1

Mechanism of Dipyridamole Action in Platelets: in Vivo Study With Healthy Volunteers

CompletedNCT02226926

Boehringer IngelheimHealthy

Start: 2000-07-31Updated: 2014-08-27

Phase 3

Aggrenox Prevention of Access Stenosis

CompletedNCT00067119

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Kidney Failure

Start: 2003-01-01End: 2008-01-31Updated: 2017-09-19

Phase 4

PRoFESS - Prevention Regimen For Effectively Avoiding Second Strokes

CompletedNCT00153062

Boehringer IngelheimStroke

Start: 2003-08-31Updated: 2014-05-13

Pharmacokinetics of Dipyridamole Administered as Aggrenox® (Dipyridamole Extended Release Plus Aspirin) Capsule Versus Dipyridamole Immediate Release Plus Aspirin Following Alteration of Stomach pH

CompletedNCT02251184

Boehringer IngelheimHealthy

Start: 2000-10-31Updated: 2014-09-29

Related Papers

Low Glomerular Filtration Rate, Recurrent Stroke Risk, and Effect of Renin–Angiotensin System Modulation

Stroke2013-08-3032 citations

Telmisartan on top of antihypertensive treatment does not prevent progression of cerebral white matter lesions in the prevention regimen for effectively avoiding second strokes (PRoFESS) MRI substudy.

2012-06-2661 citations

Risk of recurrent stroke in patients with silent brain infarction in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) imaging substudy.

2012-01-1914 citations

Level of systolic blood pressure within the normal range and risk of recurrent stroke.

2011-11-01161 citations

Effect of dipyridamole plus aspirin on hemodialysis graft patency.

2009-05-01184 citations

Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: a double-blind, active and placebo-controlled study.

2008-08-29219 citations

Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke.

2008-08-27573 citations

Telmisartan to prevent recurrent stroke and cardiovascular events.

2008-08-27502 citations

Effect of clopidogrel on early failure of arteriovenous fistulas for hemodialysis: a randomized controlled trial.

2008-05-01576 citations