Aerosolized placebo

DRUG4 trials

Sponsors

Bayer, Cardeas Pharma, Wright State University

Conditions

Pneumonia, BacterialPneumonia, Ventilator-Associated

Phase 2

Aerosolized Amikacin and Fosfomycin in Mechanically Ventilated Patients With Gram-negative Pneumonia

CompletedNCT01969799

Cardeas PharmaPneumonia, Bacterial

Start: 2013-12-31End: 2016-04-30Updated: 2017-07-02

Aerosolized Amikacin and Fosfomycin in Mechanically Ventilated Patients With Gram-negative and / or Gram-positive Bacterial Colonization

WithdrawnNCT02218359

Cardeas PharmaPneumonia, Bacterial

Start: 2014-10-31End: 2016-01-31Updated: 2015-11-18

Phase 3

Inhaled Amikacin Solution BAY41-6551 as Adjunctive Therapy in the Treatment of Gram-Negative Pneumonia

CompletedNCT01799993

BayerPneumonia, Bacterial

Start: 2013-04-13End: 2017-04-07Updated: 2018-07-23

Phase 4

Aerosolized Antibiotics in the Treatment of Ventilator Associated Pneumonia

TerminatedNCT02478710

Wright State UniversityPneumonia, Ventilator-Associated

Start: 2015-06-30End: 2022-07-31Updated: 2023-05-31

Related Papers

Inhaled amikacin adjunctive to intravenous standard-of-care antibiotics in mechanically ventilated patients with Gram-negative pneumonia (INHALE): a double-blind, randomised, placebo-controlled, phase 3, superiority trial.

2019-12-1980 citations

A Randomized Trial of the Amikacin Fosfomycin Inhalation System for the Adjunctive Therapy of Gram-Negative Ventilator-Associated Pneumonia: IASIS Trial.

2016-11-24116 citations