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adoptive immunotherapy

BIOLOGICAL6 trials

Sponsors

Prof. Serge Leyvraz, University Hospital Birmingham, National Cancer Institute (NCI), Chinese PLA General Hospital, M.D. Anderson Cancer Center

Conditions

Adoptive ImmunotherapyColorectal AdenocarcinomaGraft Versus Host DiseaseHepatocellular CarcinomaMelanoma (Skin)Metastatic CholangiocarcinomaMetastatic Colorectal CarcinomaMetastatic Digestive System Carcinoma

Phase 1

Cyclophosphamide and Fludarabine Followed by Cellular Adoptive Immunotherapy and Vaccine Therapy in Patients With Metastatic Melanoma
CompletedNCT00324623
Prof. Serge LeyvrazMelanoma (Skin)
Start: 2005-09-30Updated: 2012-11-20
Th1/Tc1 Immunotherapy Following Stem Cell Transplantation in Multiple Myeloma
TerminatedNCT01239368
National Cancer Institute (NCI)Myeloma-Multiple, Myeloma, Plasma-Cell, Myelomatosis
Start: 2010-11-10End: 2017-08-16Updated: 2019-12-10
Autologous Cytokine Induced Killer Cells (CIK) for Patients With Severe Psoriasis
CompletedNCT01894373
Chinese PLA General HospitalAdoptive Immunotherapy, Psoriasis
Start: 2015-06-30End: 2017-06-30Target: 10Updated: 2018-05-17
CD8+ T Cell Therapy and Pembrolizumab in Treating Patients With Metastatic Gastrointestinal Tumors
TerminatedNCT02757391
M.D. Anderson Cancer CenterColorectal Adenocarcinoma, Metastatic Cholangiocarcinoma, Metastatic Colorectal Carcinoma +10
Start: 2019-08-09End: 2020-10-02Updated: 2020-10-30

Phase 2

T-Lymphocyte Infusion or Standard Therapy in Treating Patients at Risk of Cytomegalovirus Infection After a Donor Stem Cell Transplant
NCT00986557
University Hospital BirminghamGraft Versus Host Disease, Nonneoplastic Condition
Start: 2009-09-30Target: 78Updated: 2013-08-26
Combination Therapy of Microwave Ablation and Cellular Immunotherapy for Hepatocellular Carcinoma
CompletedNCT02851784
Chinese PLA General HospitalHepatocellular Carcinoma
Start: 2009-12-31End: 2021-03-01Updated: 2021-03-04

Related Papers

Restoration of CD3<sup>+</sup>CD56<sup>+</sup> cell level improves skin lesions in severe psoriasis: A pilot clinical study of adoptive immunotherapy for patients with psoriasis using autologous cytokine-induced killer cells.
2018-08-095 citations
Autologous Rapamycin-Resistant T Cell Therapy of Multiple Myeloma
Biology of Blood and Marrow Transplantation2016-02-181 citations
MART-1 peptide vaccination plus IMP321 (LAG-3Ig fusion protein) in patients receiving autologous PBMCs after lymphodepletion: results of a Phase I trial.
2014-04-1270 citations