Adalimumab (Humira)

DRUG8 trials

Conditions

Ankylosing SpondylitisArthritisArthritis; BehcetCardiovascular DiseaseFocal GlomerulosclerosisHealthyJoint DiseasesPsoriasis

Phase 1

Pilot Studies of Novel Therapies to Treat Resistant Focal Segmental Glomerulosclerosis (FSGS)

CompletedNCT00193648

Northwell HealthFocal Glomerulosclerosis

Start: 2005-07-31End: 2007-10-31Updated: 2007-10-22

Comparative Clinical Study of Pharmacokinetics, Tolerance and Safety of BCD-057 and Humira in Healthy Volunteers

CompletedNCT02395055

BiocadHealthy

Start: 2015-06-30End: 2015-10-31Updated: 2021-11-05

Phase 3

An Open-Label Study to Evaluate the Response to Adalimumab in Patients With Active Ankylosing Spondylitis Who Have Failed Standard Therapy or TNF-Alpha Inhibitors (RHAPSODY)

CompletedNCT00478660

AbbottAnkylosing Spondylitis

Start: 2006-02-28Updated: 2007-10-10

Efficacy of Humira in Behcet Patients With Arthritis

CompletedNCT01497717

Rambam Health Care CampusArthritis; Behcet

Start: 2013-07-31End: 2016-10-31Updated: 2016-10-26

Phase 4

Humira in Rheumatoid Arthritis - Do Bone Erosions Heal?

CompletedNCT00696059

Hvidovre University HospitalArthritis, Joint Diseases, Rheumatoid Arthritis

Start: 2004-08-31End: 2007-07-31Updated: 2008-06-12

Mechanism of Action Study for Psoriasis

CompletedNCT00932113

Tufts Medical CenterPsoriasis

Start: 2009-06-30End: 2017-05-01Updated: 2017-08-31

Vascular Inflammation in Psoriasis Trial (The VIP Trial)

CompletedNCT01553058

University of PennsylvaniaCardiovascular Disease, Psoriasis

Start: 2012-07-31End: 2016-10-27Updated: 2018-05-22

Unknown Phase

Safety and Effectiveness and Effect on Quality of Life and Work Productivity of Humira in Patients With Psoriatic Arthritis in Clinical Routine

WithdrawnNCT01078610

AbbottPsoriatic Arthritis

Updated: 2012-08-10

PLoS ONE2022-02-076 citations

Patient-reported outcomes of adalimumab, phototherapy, and placebo in the Vascular Inflammation in Psoriasis Trial: A randomized controlled study.

2019-06-0112 citations

Effect of 2 Psoriasis Treatments on Vascular Inflammation and Novel Inflammatory Cardiovascular Biomarkers

Circulation Cardiovascular Imaging2018-05-18143 citations

Investigation of a multi-biomarker disease activity score in rheumatoid arthritis by comparison with magnetic resonance imaging, computed tomography, ultrasonography, and radiography parameters of inflammation and damage.

2016-09-2812 citations

<i>CCL20</i>and<i>IL22</i>Messenger RNA Expression After Adalimumab vs Methotrexate Treatment of Psoriasis

JAMA Dermatology2015-05-0644 citations

Clinical and economic burden of extra-articular manifestations in ankylosing spondylitis patients treated with anti-tumor necrosis factor agents.

2012-06-1134 citations

Effectiveness and safety of adalimumab in patients with ankylosing spondylitis or psoriatic arthritis and history of anti-tumor necrosis factor therapy.

2010-06-1670 citations

Effectiveness of adalimumab in treating patients with ankylosing spondylitis associated with enthesitis and peripheral arthritis.

2010-03-1521 citations

Effectiveness, safety, and predictors of good clinical response in 1250 patients treated with adalimumab for active ankylosing spondylitis.

2009-02-27152 citations

Adalimumab effectively reduces the rate of anterior uveitis flares in patients with active ankylosing spondylitis: results of a prospective open-label study.

2008-07-28170 citations