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Ad5CMV-p53 gene

BIOLOGICAL12 trials

Sponsors

National Cancer Institute (NCI), Aventis Pharmaceuticals, University of Texas Southwestern Medical Center, Eastern Cooperative Oncology Group, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Conditions

Brain and Central Nervous System TumorsBreast CancerHead and Neck CancerLip and Oral Cavity CancerLiver CancerLung CancerOropharyngeal CancerOvarian Cancer

Phase 1

Gene Therapy Plus Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer
CompletedNCT00004225
Eastern Cooperative Oncology GroupLung Cancer
Start: 2000-01-31Updated: 2010-07-07
Gene Therapy in Treating Patients With Non-small Cell Lung Cancer That Cannot Be Surgically Removed
CompletedNCT00003649
Eastern Cooperative Oncology GroupLung Cancer
Start: 1998-11-17End: 2007-06-15Updated: 2023-06-22
Gene Therapy in Preventing Cancer in Patients With Premalignant Carcinoma of the Oral Cavity or Pharynx
CompletedNCT00064103
National Cancer Institute (NCI)Lip and Oral Cavity Cancer, Oropharyngeal Cancer, Stage 0 Lip and Oral Cavity Cancer +2
Start: 2003-06-30Updated: 2013-01-23
Gene Therapy in Treating Patients With Advanced Bladder Cancer
CompletedNCT00003167
National Cancer Institute (NCI)Recurrent Bladder Cancer, Stage I Bladder Cancer, Stage II Bladder Cancer +3
Start: 1998-05-31Updated: 2013-01-23
Gene Therapy in Treating Patients With Advanced Recurrent or Persistent Ovarian Cancer or Primary Peritoneal Cancer
CompletedNCT00003450
University of Texas Southwestern Medical CenterOvarian Cancer, Peritoneal Cavity Cancer
Start: 1998-09-30End: 1999-01-31Updated: 2021-02-02
Gene Therapy Plus Chemotherapy in Treating Patients With Breast Cancer
CompletedNCT00004038
National Cancer Institute (NCI)Breast Cancer
Start: 1999-01-31Updated: 2013-02-07
Gene Therapy in Treating Patients With Recurrent Malignant Gliomas
CompletedNCT00004041
Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsBrain and Central Nervous System Tumors
Start: 1999-02-25End: 2003-07-01Updated: 2018-06-27
Gene Therapy in Treating Patients With Cancer of The Liver
TerminatedNCT00003147
National Cancer Institute (NCI)Liver Cancer
Start: 1998-02-28Updated: 2013-02-05
Gene Therapy in Treating Patients With Ovarian Cancer
CompletedNCT00003588
National Cancer Institute (NCI)Ovarian Cancer
Start: 1998-09-30Updated: 2013-02-08

Phase 2

S0011, Gene Therapy & Surgery Followed by Chemo & RT in Newly Diagnosed Cancer of the Mouth or Throat
TerminatedNCT00017173
SWOG Cancer Research NetworkHead and Neck Cancer
Start: 2003-02-28End: 2011-07-31Updated: 2012-06-14
Chemotherapy Combined With Gene Therapy in Treating Patients Who Have Stage III or Stage IV Breast Cancer
CompletedNCT00044993
Introgen TherapeuticsBreast Cancer
Start: 2002-02-28End: 2004-08-31Updated: 2013-05-30
Gene Therapy in Treating Patients With Recurrent Head and Neck Cancer
NCT00003257
Aventis PharmaceuticalsHead and Neck Cancer
Start: 1998-01-31Target: 39Updated: 2013-12-04

Related Papers

A phase 2 trial of surgery with perioperative INGN 201 (Ad5CMV-p53) gene therapy followed by chemoradiotherapy for advanced, resectable squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx: report of the Southwest Oncology Group.
2009-09-0141 citations