Active Cannabis

DRUG4 trials

Sponsors

University of California, Los Angeles, New York State Psychiatric Institute, University of California, San Diego

Conditions

Abuse, DrugBack PainCannabisChronic Low Back and Leg PainChronic Low-back Pain (cLBP)Degenerative Disc DiseaseHyperalgesiaLower Back Pain

Early Phase 1

Brain Mechanisms Supporting Cannabis-induced Pain Relief

RecruitingNCT04982965

University of California, San DiegoBack Pain, Chronic Low Back and Leg Pain, Chronic Low-back Pain (cLBP) +4

Start: 2021-05-07End: 2027-03-15Target: 100Updated: 2026-06-03

Phase 1

Cannabis Effects as a Function of Sex

Active, not recruitingNCT04385082

University of California, Los AngelesAbuse, Drug, Pain

Start: 2021-07-08End: 2027-09-01Target: 160Updated: 2026-07-06

Phase 2

Repeated Cannabis Administration on Experimental Pain and Abuse Liability

CompletedNCT04576507

New York State Psychiatric InstituteCannabis, Hyperalgesia, Pain +1

Start: 2021-06-01End: 2023-12-31Updated: 2025-08-08

Impact of Repeatedly-Administered THC-cannabis on Experimental Pain and Abuse Liability in Humans

SuspendedNCT04596644

New York State Psychiatric InstituteCannabis, Hyperalgesia, Pain +1

Start: 2021-08-01End: 2026-10-31Target: 16Updated: 2026-09-08