FindTrial
Sign In

ACTH

DRUG13 trials

Sponsors

Mayo Clinic, Neurologique Foundation, Inc., Cedars-Sinai Medical Center, Southeast Renal Research Institute, University of Southern California

Conditions

ACTHDiabetic NephropathyGout AttackIdiopathic Membranous NephropathyInfantile SpasmInfantile SpasmsKetogenic DietMenopause

Early Phase 1

Relative Contributions of Predictors of Hyperandrogenism in Older vs. Young Women With PCOS
RecruitingNCT03905603
University of VirginiaPolycystic Ovary Syndrome
Start: 2019-10-08End: 2026-05-01Target: 144Updated: 2023-11-03

Phase 1

Dose-Finding Pilot Study of ACTH in Patients With Idiopathic Membranous Nephropathy
CompletedNCT00805753
Mayo ClinicIdiopathic Membranous Nephropathy
Start: 2009-01-31End: 2014-09-30Updated: 2014-10-13
Pulse ACTH vs. MP for MS
CompletedNCT01049451
University of Southern CaliforniaMultiple Sclerosis
Start: 2009-11-30End: 2013-07-31Updated: 2017-04-19

Phase 2

Efficacy Study of Adrenocorticotropin Hormone to Treat Multiple Sclerosis (MS) Relapses After Sub-responding to an Initial 3 Day Course of Intravenous (IV) Methylprednisolone
TerminatedNCT00947895
Neurologique Foundation, Inc.Multiple Sclerosis
Start: 2009-10-31End: 2011-01-31Updated: 2016-03-22
ACTH in Progressive Forms of MS
TerminatedNCT01950234
University of MinnesotaPrimary Progressive Multiple Sclerosis, Progressive Relapsing Multiple Sclerosis, Secondary Progressive Multiple Sclerosis
Start: 2014-04-17End: 2022-12-31Updated: 2025-02-11
Ketogenic Diet vs ACTH for the Treatment of Children With West Syndrome
Active, not recruitingNCT05279118
All India Institute of Medical SciencesACTH, Infantile Spasm, Ketogenic Diet +1
Start: 2022-04-18End: 2024-07-28Target: 80Updated: 2024-06-25

Phase 3

Adrenocorticotropic Hormone (ACTH) for Frequently Relapsing and Steroid Dependent Nephrotic Syndrome
CompletedNCT02132195
Emory UniversityNephrotic Syndrome
Start: 2014-05-31End: 2018-03-31Updated: 2019-05-29
ACTH for Fatigue in Multiple Sclerosis Patients
CompletedNCT02315872
Providence Health & ServicesMultiple Sclerosis, Relapsing-Remitting
Start: 2015-05-22End: 2018-12-13Updated: 2019-09-09

Phase 4

Adrenocorticotropic Hormone (ACTH) Treatment of Nephrotic Range Proteinuria in Diabetic Nephropathy (NRDN)
CompletedNCT01028287
Southeast Renal Research InstituteDiabetic Nephropathy, Nephrotic Syndrome
Start: 2009-05-31End: 2011-07-31Updated: 2013-05-31
Evaluation of Neuroinflammation in Children With Infantile Spasms
CompletedNCT02092883
Wayne State UniversityInfantile Spasms
Start: 2013-03-31End: 2017-07-31Updated: 2017-11-07

Unknown Phase

Cortisol Levels on Menopausal Symptoms - Ancillary (Addendum) Study to Protocol 16997
CompletedNCT00950781
Cedars-Sinai Medical CenterMenopause
Start: 2009-01-31End: 2010-02-28Updated: 2019-06-07
Availability Study of ACTH to Treat Children SRNS/SDNS
NCT02972346
Xinhua Hospital, Shanghai Jiao Tong University School of MedicineProteinuria
Start: 2016-11-30End: 2019-06-30Target: 42Updated: 2016-11-23
ACTH vs Betamethasone in Hospitalized Patients With Acute Gout
NCT04306653
University of PatrasGout Attack
Start: 2018-01-05End: 2020-05-31Target: 60Updated: 2020-03-13

Related Papers

ACTH vs steroids for the treatment of acute gout in hospitalized patients: a randomized, open label, comparative study.
2022-04-212 citations
Advanced diabetic nephropathy with nephrotic range proteinuria: a pilot study of the long-term efficacy of subcutaneous ACTH gel on proteinuria, progression of CKD, and urinary levels of VEGF and MCP-1.
2013-09-1217 citations