Acetyl-L-carnitine

DRUG14 trials

Sponsors

National Institute of Allergy and Infectious Diseases (NIAID), Vanderbilt University, University of Catania, Norwegian University of Science and Technology, University of South Florida

Conditions

AcetylcarnitineAlzheimer DiseaseAmyotrophic Lateral SclerosisCarpal Tunnel SyndromeChemotherapy-induced Peripheral NeuropathyCompression NeuropathyDaily ActivityFatigue

Phase 1

Acetyl-L-Carnitine in the Treatment of Septic Shock

CompletedNCT00592488

Vanderbilt UniversitySeptic Shock

Start: 2006-08-31End: 2009-09-30Updated: 2017-12-08

Phase 2

Acetyl-l-carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome

CompletedNCT02141035

University of AlbertaCarpal Tunnel Syndrome, Compression Neuropathy

Start: 2015-09-30End: 2017-09-30Updated: 2017-10-27

Preventive Effect of Acetyl-L-carnitine on Oxaliplatin-induced Peripheral Neuropathy

Nanfang Hospital, Southern Medical UniversityAcetylcarnitine, Chemotherapy-induced Peripheral Neuropathy

Start: 2022-11-01End: 2024-12-31Target: 100Updated: 2022-11-01

Trial on the Biological and Clinical Effects of Acetyl-L-carnitine in ALS

RecruitingNCT06126315

Mario Negri Institute for Pharmacological ResearchAmyotrophic Lateral Sclerosis

Start: 2025-03-26End: 2027-09-30Target: 246Updated: 2025-09-25

Phase 3

Acetyl-L-Carnitine Supplementation During HCV Therapy With Peg IFN-α2b Plus Ribavirin: Effect on Work Performance.

CompletedNCT01909557

University of CataniaDaily Activity, Fatigue, Quality of Life

Start: 2010-01-31End: 2011-12-31Updated: 2013-07-26

Acetyl-L-Carnitine Reduces Perceived Work Stress and Improves Work Ability and Work Performance in Hepatic Encephalopathy

CompletedNCT02173132

University of CataniaWork Ability, Work Performance, Work Stress

Start: 2010-04-30Updated: 2014-06-24

Phase 4

Effect of Acetyl-L-carnitine in Migraine

CompletedNCT01695317

Norwegian University of Science and TechnologyMigraine

Start: 2013-04-30End: 2014-09-30Updated: 2022-04-13

Assessment the Efficacy of Acetyl-L-carnitine in Patient With Alzheimer's Disease

CompletedNCT02955706

Dong-A ST Co., Ltd.Alzheimer Disease

Start: 2016-04-01End: 2019-01-25Updated: 2021-04-14

Unknown Phase

Acetyl-L-Carnitine for the Treatment of NRTI-Associated Peripheral Neuropathy

CompletedNCT00050271

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Peripheral Nervous System Diseases

End: 2007-01-31Updated: 2021-11-01

Oral Acetyl-L-Carnitine Therapy Reduces Fatigue In Hepatic Encephalopathy

CompletedNCT01223742

University of CataniaHepatic Encephalopathy

Start: 2002-06-30End: 2006-12-31Updated: 2010-10-19

Acetyl-L-Carnitine Reduces Depression and Improves Quality of Life in Patients With Minimal Hepatic Encephalopathy

CompletedNCT01223729

University of CataniaMinimal Hepatic Encephalopathy

Start: 2002-04-30End: 2005-11-30Target: 67Updated: 2010-10-19

Acetyl-L-Carnitine In Severe Hepatic Encephalopathy

CompletedNCT01223768

University of CataniaHepatic Encephalopathy (Grade 3 of the West Haven Grading Scale)

Start: 2002-07-31End: 2005-12-31Updated: 2010-10-19

An Open-label Study of the Effects of Acetyl-L-Carnitine on Cardiovascular Outcomes in Friedreich's Ataxia

University of South FloridaFriedreich's Ataxia

Start: 2013-08-31End: 2017-06-30Target: 20Updated: 2016-04-12

Effects of Acetyl L-Carnitine Supplementation on Clinical, Metabolic and Inflammatory Symptoms in Obese, Diabetic, Postmenopausal Women With Osteoarthritis

CompletedNCT07660081

Khyber Medical University PeshawarObesity, Osteoarthritis, Type 2 Diabetes

Start: 2025-12-01End: 2026-08-15Updated: 2026-09-17

Related Papers

Acetyl-L-carnitine (ALCAR) to enhance nerve regeneration in carpal tunnel syndrome: study protocol for a randomized, placebo-controlled trial.

2016-04-145 citations

Acetyl-l-carnitine versus placebo for migraine prophylaxis: A randomized, triple-blind, crossover study

Cephalalgia2015-01-1923 citations

Oral acetyl-L-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study.

2011-02-1070 citations