FindTrial
Sign In

ACETAZOLAMIDE oral capsule

DRUG18 trials

Sponsors

University of Zurich, University of California, Riverside, Lucrecia Maria Burgos

Conditions

Acute Heart Failure (AHF)Acute Mountain SicknessAcute Mountain Sickness (AMS)Altitude HypoxiaChronic Obstructive Pulmonary DiseaseChronic Obstructive Pulmonary Disease (COPD)HypoxemiaImmune Response

Early Phase 1

The Role of Acetazolamide in Mitigating Inflammation and Innate Immune Activation at High Altitude
Active, not recruitingNCT07517068
University of California, RiversideAcute Mountain Sickness (AMS), Hypoxemia, Immune Response +1
Start: 2025-09-17End: 2026-12-15Updated: 2026-04-08

Phase 4

Effect Of Acetazolamide On Altitude Related Illness In Patients With Respiratory Disease
CompletedNCT03156231
University of ZurichChronic Obstructive Pulmonary Disease (COPD)
Start: 2017-05-24End: 2018-08-02Updated: 2019-01-29
Effect of Acetazolamide on Cognition in Patients With Respiratory Disease at Altitude
CompletedNCT03165890
University of ZurichChronic Obstructive Pulmonary Disease (COPD)
Start: 2017-05-24End: 2017-07-24Updated: 2019-05-14
Effect of Acetazolamide on Right Ventricular Function During Exercise in Patients With Respiratory Disease at Altitude
CompletedNCT03167034
University of ZurichChronic Obstructive Pulmonary Disease
Start: 2017-05-24End: 2018-08-02Updated: 2019-08-14
Effect of Acetazolamide on Right Ventricular Function at Rest in Patients With Respiratory Disease at Altitude
CompletedNCT03173508
University of ZurichChronic Obstructive Pulmonary Disease
Start: 2017-05-24End: 2018-08-02Updated: 2019-08-14
Effect of Acetazolamide on Postural Control in Patients With Respiratory Disease at Altitude
CompletedNCT03177811
University of ZurichChronic Obstructive Pulmonary Disease
Start: 2017-05-24End: 2018-08-02Updated: 2021-10-12
Effect of Acetazolamide on Exercise Performance in Patients With Respiratory Disease at Altitude
CompletedNCT03177837
University of ZurichChronic Obstructive Pulmonary Disease
Start: 2017-05-24End: 2018-08-02Updated: 2019-08-16
Effect of Acetazolamide on Sleep Related Breathing Disturbances in Patients With Respiratory Disease at Altitude
CompletedNCT03177850
University of ZurichChronic Obstructive Pulmonary Disease
Start: 2017-05-24End: 2018-08-02Updated: 2019-01-29
Effect of Acetazolamide on Maximal Exercise Performance in Lowlanders Older Than 40 Years at Altitude
CompletedNCT03536455
University of ZurichAltitude Hypoxia
Start: 2018-05-15End: 2018-08-02Updated: 2021-10-12
Effect of Acetazolamide on Sleep Disordered Breathing in Lowlanders Older Than 40 Years at Altitude
CompletedNCT03536507
University of ZurichAltitude Hypoxia
Start: 2018-05-15End: 2018-08-02Updated: 2021-11-05
Effect of Acetazolamide on Visuo-motor Learning in Lowlanders Older Than 40 Years at Altitude
CompletedNCT03536520
University of ZurichAltitude Hypoxia
Start: 2018-05-15End: 2018-08-02Updated: 2021-10-12
Effect of Acetazolamide on Postural Control in Lowlanders Older Than 40 Years at Altitude
CompletedNCT03536429
University of ZurichAltitude Hypoxia
Start: 2018-05-15End: 2018-08-02Updated: 2021-10-12
Effect of Acetazolamide on Right Heart Function During Exercise in Lowlanders Older Than 40 Years at Altitude
NCT03537924
University of ZurichAltitude Hypoxia
Start: 2018-06-01End: 2022-12-31Target: 100Updated: 2022-11-02
Effect of Acetazolamide on Lung Water Content by Ultrasound in Lowlanders Older Than 40 Years at Altitude
NCT03539367
University of ZurichAltitude Hypoxia
Start: 2018-06-01End: 2022-12-31Target: 100Updated: 2022-11-02
Effect of Acetazolamide on Lung Water Content by Ultrasound in Patients With Respiratory Disease at Altitude
CompletedNCT03540901
University of ZurichChronic Obstructive Pulmonary Disease
Start: 2018-05-22End: 2018-08-02Updated: 2021-11-05
Effect of Acetazolamide on Right Heart Function at Rest in Lowlanders Older Than 40 Years at Altitude.
NCT03540914
University of ZurichAltitude Hypoxia
Start: 2018-06-01End: 2024-12-31Target: 400Updated: 2023-03-10
Effect of Acetazolamide on Acute Mountain Sickness in Lowlanders Older Than 40 Years
CompletedNCT03561675
University of ZurichAcute Mountain Sickness
Start: 2018-05-15End: 2019-08-31Updated: 2021-05-13
TACTIC-HF: Sequential Diuretic Strategies in Ambulatory Worsening Heart Failure
Not yet recruitingNCT07593612
Lucrecia Maria BurgosAcute Heart Failure (AHF)
Start: 2026-06-15End: 2027-01-15Target: 60Updated: 2026-05-18

Related Papers

Nocturnal cerebral oxygenation in patients with COPD at altitude: data from a randomized clinical trial of acetazolamide.
2025-12-01
Effect of Acetazolamide on Pulmonary Hemodynamics and Right Heart Function in Healthy Adults Going to Altitude: A Randomized Controlled Trial
Journal of the American Heart Association2025-08-29
Effect of Acetazolamide on Pulmonary Hemodynamics and Right Heart Function in Healthy Adults Going to Altitude: A Randomized Controlled Trial
Universität Zürich, ZORA2025-08-29
Electrocardiographic signs of cardiac ischemia at rest and during exercise in patients with COPD traveling to 3,100 m: data from a randomized trial of acetazolamide
Frontiers in Cardiovascular Medicine2025-02-061 citations
Electrocardiographic signs of cardiac ischemia at rest and during exercise in patients with COPD traveling to 3,100 m: data from a randomized trial of acetazolamide
Universität Zürich, ZORA2025-02-06
Right ventricular strain impairment due to hypoxia in patients with COPD: a post hoc analysis of two randomised controlled trials
Universität Zürich, ZORA2025-01-04
Right ventricular strain impairment due to hypoxia in patients with COPD: a post hoc analysis of two randomised controlled trials
Open Heart2025-01-012 citations
Effect of altitude and acetazolamide on postural control in healthy lowlanders 40 years of age or older. Randomized, placebo-controlled trial
Frontiers in Physiology2024-01-045 citations
Effect of acetazolamide on visuomotor performance at high altitude in healthy people 40 years of age or older—RCT
PLoS ONE2023-01-206 citations
Effect of altitude and acetazolamide on sleep and nocturnal breathing in healthy lowlanders 40 y of age or older. Data from a randomized trial
SLEEP2022-11-1011 citations
Visuomotor performance at high altitude in COPD patients. Randomized placebo-controlled trial of acetazolamide
Frontiers in Physiology2022-09-087 citations
Acetazolamide to Prevent Adverse Altitude Effects in COPD and Healthy Adults
NEJM Evidence2021-12-2234 citations
Acetazolamide for Preventing Acute Mountain Sickness in Healthy Older than 40 years. RCT
2021-09-05
Acetazolamide effect on nocturnal oxygenation, breathing and sleep in healthy individuals older than 40 years. RCT
2021-09-05
Prevention of altitude-related illness in patients with COPD by acetazolamide. RCT
2019-09-285 citations
Effects of acetazolamide on exercise performance in patients with COPD at high altitude. RCT
2019-09-285 citations