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Acelarin
DRUG
2 trials
Sponsors
The Christie NHS Foundation Trust
, The Clatterbridge Cancer Centre NHS Foundation Trust
Conditions
Ampullary Cancer
Biliary Tract Cancer
Cholangiocarcinoma
Gallbladder Cancer
Pancreatic Acinar Carcinoma
Pancreatic Neoplasms
Phase 1
ABC-08: Phase Ib Trial of Acelarin in Combination With Cisplatin in Locally Advanced/ Metastatic Biliary Tract Cancers
Completed
NCT02351765
The Christie NHS Foundation Trust
Ampullary Cancer, Biliary Tract Cancer, Cholangiocarcinoma +1
Start: 2016-01-31
End: 2019-03-31
Updated: 2023-05-17
Phase 2
Acelarin First Line Randomised Pancreatic Study
Suspended
NCT03610100
The Clatterbridge Cancer Centre NHS Foundation Trust
Pancreatic Acinar Carcinoma, Pancreatic Neoplasms
Start: 2015-12-31
End: 2022-12-31
Target: 328
Updated: 2019-10-29
Related Papers
A Phase Ib Study of NUC-1031 in Combination with Cisplatin for the First-Line Treatment of Patients with Advanced Biliary Tract Cancer (ABC-08)
The Oncologist
2020-11-19
24 citations
NUC-1031 in combination with cisplatin for first-line treatment of advanced biliary tract cancer.
Journal of Clinical Oncology
2019-05-20
3 citations
A new ProTide, NUC-1031, combined with cisplatin for the first-line treatment of advanced biliary tract cancer (ABC-08)
Annals of Oncology
2018-10-01
8 citations
ABC-08: A phase Ib, multi-centre, open-label study of a first-in-class nucleotide analogue NUC-1031 in combination with cisplatin in patients with locally advanced/metastatic biliary tract cancers.
Journal of Clinical Oncology
2018-02-01
3 citations