Acamprosate calcium

DRUG3 trials

Sponsors

Technische Universität Dresden, National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institute of Neurological Disorders and Stroke (NINDS)

Conditions

Alcohol Use DisorderAlcoholismAmyotrophic Lateral SclerosisMotor Neuron Disease

Phase 1

Acamprosate in C9orf72 Hexanucleotide Repeat Expansion Amyotrophic Lateral Sclerosis (ACALS)

Active, not recruitingNCT07204977

National Institute of Neurological Disorders and Stroke (NINDS)Amyotrophic Lateral Sclerosis, Motor Neuron Disease

Start: 2026-02-02End: 2028-09-30Target: 30Updated: 2026-08-11

Phase 3

Investigation of the Efficacy of Acamprosate and Calcium in Comparison to Placebo as Validation of a Behavioural Test for Alcohol Dependence

CompletedNCT03634917

Technische Universität DresdenAlcoholism

Start: 2020-08-05End: 2024-05-01Updated: 2024-05-29

Phase 4

Temporally-Resolved Electrophysiology of Acamprosate Treatment of Alcohol Use Disorder

RecruitingNCT06269627

National Institute on Alcohol Abuse and Alcoholism (NIAAA)Alcohol Use Disorder

Start: 2025-05-07End: 2026-12-31Target: 48Updated: 2026-09-03