ABT-874

BIOLOGICAL7 trials

Sponsors

Abbott, AbbVie (prior sponsor, Abbott)

Conditions

Crohn's DiseaseHealthyModerate to Severe Plaque PsoriasisPlaque PsoriasisPsoriasis

Phase 1

Phase 1 BA Study, Single Center With Healthy Volunteers

CompletedNCT00870948

Start: 2009-01-31Updated: 2010-11-08

Phase 2

Dose Ranging Study Comparing the Efficacy, Safety and Pharmacokinetics of Intravenous Infusions of ABT-874 vs Placebo in Subjects With Active Crohn's Disease

TerminatedNCT00562887

AbbottCrohn's Disease

Start: 2007-11-30Updated: 2011-08-23

Phase 3

A Study Comparing the Safety and Efficacy of Two Dosing Regimens of ABT-874 to Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis

CompletedNCT00570986

AbbVie (prior sponsor, Abbott)Plaque Psoriasis

Start: 2007-11-30End: 2009-06-30Updated: 2013-02-08

Open Label Continuation Study in Moderate to Severe Psoriasis

CompletedNCT00626002

AbbVie (prior sponsor, Abbott)Moderate to Severe Plaque Psoriasis

Start: 2008-02-29End: 2011-10-31Updated: 2013-01-30

A Study of Safety and Efficacy Comparing ABT-874 Versus Methotrexate in Subjects With Moderate to Severe Plaque Psoriasis

CompletedNCT00679731

AbbVie (prior sponsor, Abbott)Psoriasis

Start: 2008-04-30End: 2009-11-30Updated: 2013-01-29

Study Comparing the Efficacy and Safety of ABT-874 to Etanercept and Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis

CompletedNCT00691964

AbbVie (prior sponsor, Abbott)Plaque Psoriasis

Start: 2008-05-31End: 2009-03-31Updated: 2013-01-21

Study Comparing the Efficacy and Safety of ABT-874 to Etanercept and Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis

CompletedNCT00710580

AbbVie (prior sponsor, Abbott)Moderate to Severe Plaque Psoriasis

Start: 2008-07-31End: 2009-04-30Updated: 2013-01-18

Related Papers

Poor early response to methotrexate portends inadequate long-term outcomes in patients with moderate-to-severe psoriasis: Evidence from 2 phase 3 clinical trials.

2017-10-064 citations

A 52-week trial comparing briakinumab with methotrexate in patients with psoriasis.

2011-10-01132 citations

Efficacy and safety of briakinumab vs. etanercept and placebo in patients with moderate to severe chronic plaque psoriasis.

2011-08-0494 citations

Efficacy and safety results from a phase III, randomized controlled trial comparing the safety and efficacy of briakinumab with etanercept and placebo in patients with moderate to severe chronic plaque psoriasis.

2011-07-28108 citations