ABT-450/r/ABT-267
Sponsors
AbbVie
Conditions
Absolute BioavailabilityChronic Hepatitis CChronic Hepatitis C InfectionChronic Hepatitis C Virus (HCV)Chronic Hepatitis C Virus (HCV) Infection Genotype 1Compensated Cirrhosis and Non-cirrhoticsHealthy VolunteerHepatitis C Virus
Phase 1
Bioavailability of ABT-450 and ABT-267 With Ritonavir
CompletedNCT02052362
Start: 2014-01-31End: 2014-02-28Updated: 2014-02-19
Pharmacokinetics and Safety of the Co-administration of ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 in Healthy Chinese Subjects
CompletedNCT02534870
Start: 2015-09-30End: 2015-09-30Updated: 2015-10-19
Phase 2
An Open-label, Single Arm, Phase 2 Study to Evaluate ABT-450/r/ABT-267 and ABT-333 With Ribavirin (RBV) in Adults With Genotype 1 HCV Infection Taking Methadone or Buprenorphine
CompletedNCT01911845
Start: 2013-04-30End: 2014-09-30Updated: 2018-05-30
A Multipart, Open-label Study to Evaluate the Safety and Efficacy of ABT-450/r/ABT-267 With and Without ABT-333 Coadministered With and Without Ribavirin in Adult With Genotype 1 or 4 Hepatitis C Virus (HCV) Infection and Human Immunodeficiency Virus, Type 1 Coinfection
CompletedNCT01939197
Start: 2013-08-30End: 2016-10-25Updated: 2021-07-12
Phase 3
Study to Evaluate the Efficacy and Safety of ABT-450/Ritonavir/ABT- 267 (ABT-450/r/ABT-267) in Japanese Adults With Genotype 2 Chronic Hepatitis C Virus (HCV) Infection
CompletedNCT02023112
Start: 2014-01-31End: 2015-09-30Updated: 2021-07-30
Study to Evaluate the Efficacy and Safety of ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) in Japanese Adults With Subgenotype 1b Chronic Hepatitis C Virus (HCV) Infection
CompletedNCT02023099
Start: 2013-12-31End: 2015-10-31Updated: 2018-06-06
A Study to Evaluate Long-term Outcomes Following Treatment With ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 With or Without Ribavirin (RBV) in Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection
CompletedNCT02167945
Start: 2014-06-12End: 2021-05-13Updated: 2022-07-19
A Study to Evaluate Long-term Outcomes Following Treatment With ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 With or Without Ribavirin (RBV) in Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection
CompletedNCT02219490
Start: 2014-10-30End: 2021-05-13Updated: 2023-04-07
ABT-450/Ritonavir/ ABT-267 (ABT-450/r/ABT-267) and ABT-333 Co-Administered With Ribavirin (RBV) in Treatment Naïve and Treatment Experienced Asian Adults With Genotype 1b Chronic Hepatitis C Virus (HCV) Infection and Compensated Cirrhosis
CompletedNCT02517528
Start: 2015-07-20End: 2017-03-16Updated: 2018-10-09