ABBV-932
Sponsors
AbbVie
Conditions
Bipolar DisorderBipolar Disorder (BPD)Bipolar I DisorderBipolar I or II DisorderBipolar II DisorderGeneralized Anxiety Disorder (GAD)Healthy ParticipantsHealthy Volunteer
Phase 1
Study to Assess Adverse Events and How ABBV-932 Oral Capsules Moves Through the Body of Healthy Adult Participants
CompletedNCT05738850
Start: 2023-02-15End: 2024-05-31Updated: 2024-07-01
A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of ABBV-932 in Healthy Adult Participants, Participants With Generalized Anxiety Disorder (GAD) and Participants With Bipolar Disorder (BPD)
CompletedNCT06024239
Start: 2023-08-31End: 2025-03-04Updated: 2025-03-17
Study of Oral ABBV-932 Capsules to Evaluate Dopamine D2 and D3 Receptor Occupancy in Brain in Adult Healthy Volunteers
CompletedNCT06300580
Start: 2024-08-21End: 2025-05-26Updated: 2025-06-05
A Study to Assess the Relative Bioavailability of Oral ABBV-932 in Healthy Adult Participants
CompletedNCT06849791
Start: 2025-02-26End: 2026-05-08Updated: 2026-06-04
A Mass Balance Study of Oral [14C] ABBV-932 in Healthy Adult Male Participants
Active, not recruitingNCT06953934
Start: 2026-05-04End: 2026-09-01Updated: 2026-06-29
Study to Assess the Adverse Events, Tolerability, and How Oral Doses of ABBV-932 Moves Through the Body in Healthy Adult Chinese Participants
CompletedNCT07024797
Start: 2025-08-21End: 2025-12-08Updated: 2025-12-31
A Study to Assess Adverse Events and How Oral ABBV-932 Moves Through the Body When Given With Oral Itraconazole in Adult Participants With Bipolar Disorder
RecruitingNCT07071532
Start: 2026-08-20End: 2027-02-01Target: 20Updated: 2026-09-16
Phase 2
Study of Oral ABBV-932 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Bipolar I or II Disorder
CompletedNCT06605599
Start: 2024-10-15End: 2025-12-10Updated: 2026-01-12
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
RecruitingNCT06846320
Start: 2025-04-29End: 2026-11-01Target: 315Updated: 2026-06-17
Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II Disorder
RecruitingNCT07220460
Start: 2025-09-30End: 2027-04-01Target: 200Updated: 2026-06-18