ABBV-382
Sponsors
AbbVie Deutschland GmbH & Co. KG, AbbVie
Conditions
HIV infectionHealthy VolunteerHuman Immuno-deficiency Virus (HIV) DiseaseHuman Immunodeficiency Virus (HIV)Moderate to Severe Crohn’s Disease
Phase 1
Study to Assess Adverse Events and How Intravenous (IV) or Subcutaneous (SC) ABBV-382 Moves Through the Body of Adult Participants With Human Immuno-Deficiency Virus (HIV-1)
CompletedNCT04554966
Start: 2021-04-16End: 2023-08-14Updated: 2024-03-04
A Study to Evaluate Adverse Events and How the Drug Moves Through the Body From Subcutaneous (SC) and Intravenous (IV) Doses of ABBV-382 in Healthy Adult Chinese Volunteers
CompletedNCT06632938
Start: 2024-10-08End: 2025-05-15Updated: 2025-05-30
Phase 2
A Study to Assess Change in Disease Activity, Adverse Events, and How the Drug Moves Through the Body in Adult Participants Living With Human Immunodeficiency Virus (HIV) Receiving Intravenous (IV) Infusion or Subcutaneous (SC) Injection of Budigalimab and/or ABBV-382
TerminatedNCT06032546
Start: 2023-10-12End: 2025-09-22Updated: 2025-10-29
A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-controlled Study to Evaluate Efficacy, Safety, Tolerability, and Pharmacokinetics of Budigalimab and/or ABBV-382 in People Living with HIV on Stable Antiretroviral Therapy Undergoing Analytical Treatment Interruption.
CompletedCTIS2023-505900-53-00
Start: 2024-04-08End: 2025-09-08Target: 32Updated: 2025-09-15
A Phase 2a Multicenter, Randomized, Platform Study of Targeted Therapies for the Treatment of Adult Subjects with Moderate to Severe Crohn’s Disease
RecruitingCTIS2024-513009-30-00
Start: 2024-11-21Target: 572Updated: 2025-10-14