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ABBV-066

DRUG16 trials

Sponsors

Abbvie Deutschland GmbH & Co. KG, AbbVie Deutschland GmbH & Co. KG, AbbVie

Conditions

Crohn's diseaseCrohn's DiseaseCrohn's diseaseCrohns DiseaseHealthyJuvenile Psoriatic ArthritisModerate to Severe Crohn’s DiseasePlaque Psoriasis

Phase 1

Phase 2

Phase 3

OptIMMize-2: A Phase 3 Multicenter, Single-arm, Open-label Extension Study to Assess the Safety, Tolerability, and Efficacy of Risankizumab in Subjects With Moderate to Severe Plaque Psoriasis Who Have Completed Participation in Study M19-977 (OptIMMize-1).
RecruitingCTIS2022-500408-22-00
Abbvie Deutschland GmbH & Co. KGPlaque Psoriasis
Start: 2022-09-14Target: 70Updated: 2025-12-15
A Phase 3, Multicenter, Randomized, Efficacy Assessor-Blinded Study of Risankizumab Compared to Ustekinumab for the Treatment of Adult Subjects With Moderate to Severe Crohn's Disease Who Have Failed Anti-TNF therapy
Active, not recruitingCTIS2022-501645-70-00
Abbvie Deutschland GmbH & Co. KGCrohns Disease
Start: 2020-11-25Target: 208Updated: 2025-10-22
OptIMMize-1: A Randomized, Active-controlled, Efficacy Assessor-blinded Study to Evaluate Pharmacokinetics, Safety, and Efficacy of Risankizumab in Patients From 6 to Less Than 18 Years of Age With Moderate to Severe Plaque Psoriasis
CompletedCTIS2023-504156-10-00
Abbvie Deutschland GmbH & Co. KGPlaque Psoriasis.
Start: 2021-08-13End: 2024-10-01Target: 72Updated: 2024-11-25
A Phase 3, Multi-Center Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Risankizumab with Open-Label Induction, Randomized Double-Blind Maintenance, and Long-Term Extension Periods in Pediatric Subjects (2 to < 18 Years of Age) with Moderately to Severely Active Crohn's Disease
RecruitingCTIS2022-502050-14-00
Abbvie Deutschland GmbH & Co. KGCrohn's disease
Start: 2024-06-04Target: 59Updated: 2026-01-16
A Phase 3, Randomized, Double-Blind Study Comparing Risankizumab to Placebo in Subjects with Active Psoriatic Arthritis Including Those Who Have a History of Inadequate Response or Intolerance to Biologic Therapy(ies) (KEEPsAKE 2)
Active, not recruitingCTIS2023-505477-33-00
AbbVie Deutschland GmbH & Co. KGPsoriatic Arthritis
Start: 2019-06-18Target: 133Updated: 2025-11-20
A Phase 3, Randomized, Double-Blind, Study Comparing Risankizumab to Placebo in Subjects with Active Psoriatic Arthritis (PsA) Who Have a History of Inadequate Response to or intolerance to at Least One Disease Modifying Anti-Rheumatic Drug (DMARD) Therapy (KEEPsAKE 1)
Active, not recruitingCTIS2023-505478-14-00
AbbVie Deutschland GmbH & Co. KGPsoriatic Arthritis
Start: 2019-05-09Target: 337Updated: 2026-01-15
Open-label, randomized, assessor-blinded, efficacy, safety, tolerability, and pharmacokinetics study of subcutaneous risankizumab with an adalimumab reference arm in children with active juvenile psoriatic arthritis
RecruitingCTIS2023-506026-36-00
AbbVie Deutschland GmbH & Co. KGJuvenile Psoriatic Arthritis
Start: 2024-04-29Target: 24Updated: 2025-09-29
A Multicenter, Randomized, Double-Blind, Placebo- Controlled 52-Week Maintenance and an Open-Label Extension Study of the Efficacy and Safety of Risankizumab in Subjects with Crohn's Disease
Active, not recruitingCTIS2023-506399-28-00
AbbVie Deutschland GmbH & Co. KGCrohn's Disease
Start: 2017-11-08Target: 387Updated: 2025-12-03
A Multicenter, Randomized, Double-Blind, Placebo Controlled 52-Week Maintenance and an Open-Label Extension Study of the Efficacy and Safety of Risankizumab in Subjects with Ulcerative Colitis
Active, not recruitingCTIS2023-506994-36-00
AbbVie Deutschland GmbH & Co. KGUlcerative Colitis
Start: 2018-10-11Target: 544Updated: 2026-01-19
A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Efficacy and Safety of Risankizumab Subcutaneous Induction Treatment in Subjects with Moderately to Severely Active Crohn’s Disease
Active, not recruitingCTIS2024-516023-13-00
AbbVie Deutschland GmbH & Co. KGCrohn's disease
Start: 2025-01-23Target: 31Updated: 2025-09-03
A Phase 3b, Multicenter, Randomized, Open-Label Study of Risankizumab Compared to Vedolizumab for the Treatment of Adult Subjects With Moderate to Severe Ulcerative Colitis Who are Naïve to Targeted Therapies
RecruitingCTIS2024-518998-33-00
AbbVie Deutschland GmbH & Co. KGUlcerative Colitis
Start: 2025-07-23Target: 293Updated: 2026-01-19
A Phase 3, Multi-Center Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Risankizumab with Open-Label Induction, Randomized Double-Blind Maintenance, and Open-Label Long-Term Extension Periods in Pediatric Subjects (2 to < 18 Years of Age) with Moderately to Severely Active Ulcerative Colitis
RecruitingCTIS2024-514695-41-00
AbbVie Deutschland GmbH & Co. KGUlcerative Colitis
Start: 2025-10-17Target: 33Updated: 2025-09-03

Phase 4

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