Abacavir (ABC)

DRUG3 trials

Sponsors

Columbia University, University of Edinburgh, University College, London

Conditions

Aicardi-Goutières SyndromeHIV InfectionHIV InfectionsHIV/AIDS

Phase 2

Inhibition of Reverse Transcription in Aicardi-Goutières Syndrome

CompletedNCT04731103

University of EdinburghAicardi-Goutières Syndrome

Start: 2022-08-24End: 2024-03-11Updated: 2024-05-09

Phase 3

Treatment Options for Protease Inhibitor-exposed Children

CompletedNCT01146873

Columbia UniversityHIV/AIDS, HIV Infections

Start: 2010-07-31End: 2014-12-31Updated: 2017-03-13

An Adaptive Platform Trial for Evaluation of Novel Treatment Regimens in Children and Adolescents With HIV in Africa

Not yet recruitingNCT07792096

University College, LondonHIV Infection

Start: 2026-11-01End: 2029-12-01Target: 800Updated: 2026-08-28

Related Papers

Reverse transcriptase inhibitors in Aicardi–Goutières syndrome: A crossover clinical trial

Developmental Medicine & Child Neurology2024-12-044 citations

Switching to Efavirenz Versus Remaining on Ritonavir-boosted Lopinavir in Human Immunodeficiency Virus-infected Children Exposed to Nevirapine: Long-term Outcomes of a Randomized Trial

Clinical Infectious Diseases2017-04-1129 citations

Efavirenz-Based Antiretroviral Therapy Among Nevirapine-Exposed HIV-Infected Children in South Africa

JAMA2015-11-0341 citations