8-Chloroadenosine

DRUG2 trials

Sponsors

City of Hope Medical Center

Conditions

Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeRecurrent Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia

Phase 1

8-Chloroadenosine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

CompletedNCT02509546

City of Hope Medical CenterAcute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia

Start: 2015-09-02End: 2021-03-16Updated: 2023-12-05

8-Chloroadenosine in Combination With Venetoclax for the Treatment of Patients With Relapsed/Refractory Acute Myeloid Leukemia

RecruitingNCT05263284

City of Hope Medical CenterAcute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia

Start: 2022-10-31End: 2029-01-25Target: 30Updated: 2026-08-21

Related Papers

Targeting the Methionine-MAT2A-SAM Axis of Acute Myeloid Leukemia with a Combination of Venetoclax and 8-Chloro-Adenosine or 8-Amino-Adenosine

Blood2022-11-15